New mouthwash formula aims to fight plaque on dental implants

NCT ID NCT06770114

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new mouthwash containing CPC, hyaluronic acid, and zinc lactate against a standard fluoride mouthwash. The goal was to see if it reduces plaque and prevents gum problems in adults with at least two dental implants. Eighty participants used the mouthwash for six months, and researchers measured gum inflammation and plaque levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mouthwash containing cetylpyridinium chloride, hyaluronic acid, and zinc lactate

What this could lead to

If it works, this could offer a new option for people with dental implants to better control plaque and gum inflammation.

What could go wrong

This is a small, completed Phase 3 trial with only 80 participants, so results may not apply to everyone. The improvement over standard fluoride mouthwash may be modest.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinica Odontoiatrica Montesani

    Roma, Rome, 00187, Italy