ENDOMETRIOSIS

This study looks at whether having surgery to remove deep endometriosis from the bowel before IVF helps women with infertility get pregnant. About 120 women with painful symptoms and trouble conceiving will be randomly assigned to either surgery followed by IVF or IVF alone. The …

This study tests whether a newer surgical method called argon plasma coagulation (APC) is gentler on the ovaries than the standard cyst removal surgery for ovarian endometriomas (chocolate cysts) caused by endometriosis. Seventy-two women will be randomly assigned to receive eith…

This study tests whether the da Vinci Xi robot can safely perform various surgeries in children aged 6 to 21. The goal is to see if robotic surgery works as well as traditional methods for conditions like gallbladder removal or endometriosis. Researchers will track how often the …

This study tests whether drinking a special nutritional supplement before bladder removal surgery (cystectomy) can reduce infections and other complications within 30 days. About 232 adults in Switzerland will take part, with half receiving the supplement and half receiving stand…

This study looks at whether giving a GnRH agonist before a frozen embryo transfer can help women with endometriosis or adenomyosis get pregnant. About 180 women aged 18 to 36 will be randomly assigned to receive either standard hormone support or standard support plus one or two …

This study tests whether a natural supplement called Indinol Forto works as well as the standard hormone drug Visanne for reducing pelvic pain caused by endometriosis. About 290 women aged 18 to 45 who have been diagnosed with endometriosis through surgery will take one of the tw…

This study looks at 350 women under 39 with advanced endometriosis (stage III-IV) who want to get pregnant. Half will have surgery to remove endometriosis tissue before trying IVF, and the other half will go straight to IVF. The goal is to see which approach leads to more live bi…

This study tests whether a drug called goserelin acetate, which temporarily stops menstruation, can reduce fat buildup in the liver of women with endometriosis. The drug creates a short-term menopause-like state. Researchers will measure liver fat and stiffness using ultrasound. …

This study aims to find markers in menstrual blood that can diagnose endometriosis, a painful condition affecting many women. Researchers will compare menstrual blood from 250 women with and without endometriosis, and also look at samples before and after surgery in some patients…

This study explores whether a total-body PET/CT scan can identify endometriosis without the need for surgery. About 30 women with suspected endometriosis will receive two scans using special tracers that highlight bleeding and scarring. The scan results will be compared with find…

This study is testing a new, non-invasive lab test that uses menstrual blood to diagnose endometriosis. Currently, diagnosis requires surgery, which can take years to get. The study will enroll 200 women aged 14-49 to see how accurate the test is compared to standard methods.

This study tests a new blood test called HerResolve™ to see if it can accurately detect endometriosis in women aged 18 to 49 who have symptoms like pelvic pain or abnormal bleeding. About 100 participants will give a blood sample before their scheduled laparoscopy (a surgical pro…

This study is testing whether a special PET scan called 18F-FES PET/CT can find endometriosis lesions more accurately than standard MRI. The scan measures estrogen receptors in the lesions, which may help doctors understand pain levels and guide treatment. About 20 women with end…

This study is testing whether a special PET/MRI scan can accurately diagnose endometriosis. Researchers will scan 24 women who are scheduled for surgery to check for endometriosis. The goal is to see if the scan can find or rule out the disease without needing an operation.

This study tests a program that combines gentle exercise with pain education for women with endometriosis. The goal is to reduce chronic pain and improve daily life, including movement and sexual function. 62 women will be split into two groups: one gets the full program, the oth…

This study looks at whether practicing yoga can reduce pain caused by endometriosis in women aged 18 to 45. Participants must have had surgery-confirmed endometriosis and moderate to severe pain. They will do yoga sessions and report their pain levels using questionnaires. The go…

This study compares a home pelvic floor physical therapy program to standard care for 30 women having endometriosis surgery (without hysterectomy). Participants will report their pain and quality of life over the recovery period. The goal is to see if a simple home program can ea…

This study tests whether pulsed electromagnetic field therapy (PEMF) can reduce pain and improve quality of life in women with endometriosis. Sixty women aged 18-45 with chronic pelvic pain will receive either real or sham PEMF treatments for 8 weeks, while continuing their usual…

This study tests whether a single mindfulness session before endometriosis surgery can help reduce pain and the need for painkillers afterward. About 20 adults with endometriosis will either get the mindfulness session plus usual care, or just education plus usual care. Researche…

This study tests whether metformin, a common diabetes drug, can reduce pelvic pain in young women with endometriosis. Fourteen participants will take either metformin or a placebo daily for 6 months and track their symptoms. The goal is to see if this non-hormonal approach offers…

This study tests whether live, online yoga classes (Tele-Yoga) can reduce chronic pelvic pain, fatigue, and improve quality of life in women with endometriosis. About 66 women will be randomly assigned to either Tele-Yoga or usual care. The goal is to see if a gentle, home-based …

This study tests whether a whole food plant-based diet can reduce pain in women with endometriosis. 120 women aged 18-45 with moderate to severe pelvic pain will be randomly assigned to either follow the special diet or stay on their usual diet for 12 weeks. The goal is to see if…

This pilot study tests if using a dye to see the ureters during endometriosis surgery causes less pain than the usual plastic stents. About 70 women with deep endometriosis will take part. The goal is to see if this approach is possible and acceptable before a larger study.

This study tests a small, battery-powered device called TENS that sends mild electrical pulses through the skin to help manage pelvic pain from endometriosis. About 92 women with chronic pelvic pain will use the device daily for 4 weeks, and some will get a sham device for compar…

This study tests an internet-based therapy program for 10 people with endometriosis and chronic pain. The program teaches skills like mindfulness and acceptance to help reduce pain's impact on daily life. Participants work online with a psychologist over several weeks. The goal i…

This study looks at whether changing what you eat and taking probiotics can help reduce chronic pelvic pain in women who have both endometriosis and irritable bowel syndrome (IBS). Researchers will enroll 74 women aged 18 to 50 and randomly assign them to different groups to comp…

This study tests whether an educational podcast can improve quality of life for people with chronic pelvic pain or endometriosis. About 100 participants will either receive standard care alone or standard care plus access to a podcast series. Over six months, everyone fills out t…

This study tests whether a wearable device called NettleEndo, which delivers mild electrical stimulation to the brain, can reduce chronic pelvic pain in women with endometriosis. About 120 women will use the device at home for 20 minutes a day, five days a week, for 12 weeks. Hal…

This study compares two types of surgery for people with deep endometriosis and adenomyosis who need a hysterectomy. It looks at whether robot-assisted surgery leads to fewer complications than standard laparoscopic surgery. The goal is to find which approach is safer and improve…

This study tests whether a series of workshops led by different health experts, plus regular nurse phone calls, can improve quality of life for women with endometriosis. About 260 women with confirmed endometriosis and chronic pelvic pain will take part. The program focuses on ed…

This study tests whether a gentle, non-invasive device that stimulates a nerve in the ear can reduce chronic pelvic pain in women with endometriosis. The device is thought to calm inflammation and change brain chemicals involved in pain. About 72 women will use the device and rep…

This study tests a new drug called vipoglanstat to see if it can reduce pelvic pain in people with endometriosis. About 190 women aged 18 to 44 with moderate to severe pain will take either the drug or a placebo for four months. The goal is to find a better treatment option for t…

This study tests whether a special pain consultation and education session can help women with endometriosis feel more in control of their pain and improve their quality of life. About 110 women will either receive the new consultation plus usual care, or usual care alone. They w…

This study is testing whether a custom CBD product can reduce pain and other symptoms in people with endometriosis. About 30 participants will receive either the CBD product or a placebo for 12 weeks. The goal is to see if this cannabinoid-based treatment offers relief for a cond…

This study looks at whether combining pain neuroscience education with therapeutic exercise can reduce pain, improve quality of life, and lower pain-related distress in women with endometriosis. About 32 adult women diagnosed with endometriosis will take part. Researchers will tr…

This study compares a newer surgical technique (IDLnR) with standard laparoscopic surgery for women with bowel endometriosis. About 192 premenopausal women aged 18-55 with confirmed bowel endometriosis and bowel symptoms will be randomly assigned to one of the two surgeries. The …

This study tests a new 8-week group program called PEEPS for women aged 18-48 with endometriosis-related chronic pelvic pain. Participants join weekly sessions combining education, peer support, and integrative care. The goal is to see if this approach reduces how much pain inter…

This study tests whether a low-fat plant-based diet can reduce pain and improve quality of life in women with endometriosis. 120 women aged 18-45 with confirmed endometriosis will either follow the diet or stay on their usual diet for 12 weeks. Researchers will measure changes in…

This study aims to see if brain imaging can predict which women with severe endometriosis will experience pain relief after surgery. Researchers will scan the brains of 100 women before their operation and then check their pain levels a year later. The goal is to better understan…

This study follows 5300 women aged 18-42 with endometriosis or adenomyosis to see if these conditions get worse over time. Researchers will track pain, bleeding, fertility, and use imaging to monitor changes. They also want to understand the immune system and gut bacteria's role …

This study looks at whether a physical measurement called anogenital distance (AGD) and certain hormones (testosterone and oxytocin) differ between women with severe endometriosis and those without the condition. Researchers will measure AGD, take blood and saliva samples, and as…

This study follows 650 women with endometriosis who want to have children after diagnosis. Researchers compare pregnancy rates and the need for fertility treatments between those who had surgery and those who took medication. The goal is to understand which approach leads to bett…

This research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…

This study looks at how pesticides and the bacteria living in the gut and reproductive organs may be linked to infertility in women with endometriosis. Researchers will measure DNA damage and compare these factors between 160 women with and without the condition. The goal is to f…

This study is building a national registry to collect data on people with parietal endometriosis, a condition where endometriosis tissue grows in the abdominal wall. Researchers will track those treated with either surgery or a less invasive technique called cryoablation (freezin…

This study aims to collect detailed information from 1,000 people in the UK who have endometriosis, a chronic pain condition affecting 1 in 10 women. Participants will use a mobile app to track symptoms, provide biological samples, and wear a smartwatch to monitor sleep and activ…

This study looks at endometriosis and adenomyosis, two conditions that affect women's reproductive health. The goal is to find better ways to diagnose these conditions early using a mix of genetic tests, imaging, and artificial intelligence. Researchers will study 530 women, incl…

This study looks at stem cells from menstrual blood and immune system changes in women with endometriosis. Researchers want to understand what goes wrong at the cell level to find new ways to diagnose and treat the disease. About 40 women aged 18-45 will provide samples and answe…

This study follows 200 adult women who visit the gynecological emergency department for endometriosis or related symptoms. Researchers want to see if emergency care leads to proper follow-up, like specialist visits or imaging. The goal is to understand how well the emergency syst…

This study examines how different ovarian stimulation protocols affect blood clotting and clot breakdown in women with infertility. Researchers will compare clotting properties before and after treatment in 300 participants. The goal is to understand risks and improve safety for …

This study aims to understand how a hormone-suppressing drug called Relugolix Combination Therapy affects pelvic pain, inflammation, and pain sensitivity in women with moderate-to-severe endometriosis. Researchers will measure changes in blood markers and brain activity to see ho…

This study tests whether a new smartphone app called elleFA can help women with endometriosis track their symptoms and communicate better with their doctors. Twenty pre-menopausal women aged 18 and older will use the app for 6 months, completing monthly surveys and optional daily…

This study looks at whether a simple, noninvasive eye scan can detect signs of inflammation in women with endometriosis. Researchers will compare retinal images from 100 women—half with endometriosis and half without. The goal is to see if the eyes can provide a new way to assess…

This study looks at how certain immune cells and inflammatory molecules differ in people with migraine compared to those without. Researchers will include women aged 18-50, some with migraine and some with autoimmune diseases like multiple sclerosis or rheumatoid arthritis. The g…

This study looks at 100 women aged 18-39 with severe deep endometriosis to see how surgery impacts their ovarian reserve, measured by AMH levels over 12 months. Researchers want to know if the procedure lowers egg supply, which could help doctors decide when to recommend egg free…

This study aims to create a realistic model of the endometrium in the lab using tissue from 90 women with and without endometriosis. The goal is to test how well different hormone treatments work for each person, so doctors can choose the best therapy with fewer side effects. Par…

This study listens to 150 people with endometriosis across Europe to understand how they manage their symptoms day-to-day. Through diaries, interviews, and group discussions, researchers want to learn what makes people feel empowered or abandoned. The goal is to improve support f…

This study looks at how well pelvic organs move in women with endometriosis using dynamic MRI. Researchers want to see if measuring this movement can help diagnose the disease better and explain why some treatments don't work. About 52 women with suspected endometriosis will take…

This study follows 15,000 women with endometriosis for up to 10 years to see how well different medical and surgical treatments work over time. Researchers will track symptoms, quality of life, disease return, and pregnancy rates. The goal is to learn which treatments help most i…

This study tests a surgical tool called CUSA Clarity that uses ultrasound to selectively remove endometriosis cyst lining while leaving healthy ovary tissue intact. Researchers will examine cyst wall samples from 10 women to see if the tool can spare ovarian tissue, which may hel…

This study looks at how the uterus absorbs fluid during early pregnancy, which may affect fertility. Researchers will compare tissue samples from women with and without endometriosis or infertility. The goal is to understand the role of certain proteins in this process. 140 healt…