ENDOMETRIOSIS

This study looked at two ways to manage rectal endometriosis in women aged 35-50 who do not plan to get pregnant. One group received hormone therapy for 24 months, while the other had surgery followed by hormones. The goal was to see which approach leads to better digestive funct…

This study looked at 130 women with endometriosis who had their eggs frozen for future use. Researchers compared a medication called dienogest to standard hormone treatments to see if it worked just as well for collecting mature eggs. The goal was to find a simpler, possibly safe…

This study looked at over 1100 women who had surgery for ovarian endometrioma (a type of cyst caused by endometriosis). After surgery, they took one of four hormone treatments for at least six months. The goal was to see which treatment best prevented the cysts from returning wit…

This study looked at whether measuring two tiny molecules in the blood (microRNA-125b-5p and microRNA-141-3p) can accurately diagnose early-stage endometriosis. Sixty women with symptoms like pelvic pain or infertility provided blood samples and underwent standard laparoscopic su…

This study looked at whether PET scans can better detect endometriosis lesions before surgery compared to standard MRI and ultrasound. Fifteen women with symptomatic endometriosis scheduled for surgery received a PET scan, and the results were compared with what surgeons actually…

This study tested a new saliva test to diagnose endometriosis, a painful condition affecting the uterus. Researchers collected saliva from over 1,100 women aged 18-43 with confirmed or suspected endometriosis. The goal was to see if the test could accurately detect the disease, p…

This study tested two drugs—letrozole and danazol—to see which one better reduces pain in women with endometriosis. 60 women aged 18-45 with moderate to severe pelvic pain took part. The goal was to measure how much their pain scores dropped during the study.

This study tested two pelvic floor muscle strengthening methods—EMG-biofeedback and rebound therapy (gentle bouncing)—in 42 women with endometriosis. The goal was to see which better reduces pain, improves muscle strength, and boosts quality of life. Participants had moderate to …

This study looked at whether following a healthy diet, based on the Alternative Healthy Eating Index, could help reduce pain and improve quality of life in women with endometriosis. 109 women with confirmed endometriosis and significant pain took part. Researchers measured pain l…

This study tested a 3-month online program called PelvicSense to see if it helps reduce pain and improve sexual well-being in people with endometriosis. Twelve adults with a formal diagnosis took part entirely from home. Researchers measured pain intensity and other factors befor…

This study tested a drug called cabergoline to see if it can safely reduce chronic pain from endometriosis without using hormones. 129 women aged 15 to 40 with confirmed endometriosis and ongoing pelvic pain took part. The goal was to find a new, non-surgical way to ease pain and…

This study tested a type of hand acupuncture called Korean manupuncture to see if it can reduce pain in women with endometriosis. 74 women with endometriosis were randomly assigned to receive either real hand acupuncture or a placebo. The goal was to measure changes in pain level…

This study tested whether a 12-week adapted physical activity program could improve health-related quality of life for women with endometriosis. Fifty-one women in Martinique participated. The goal was to see if regular, gentle exercise can help reduce pain and fatigue, and impro…

This study tested whether an 8-week online yoga program could reduce pain and improve quality of life in women with endometriosis. 52 women took part, comparing yoga to a standard physical exercise routine. The goal was to see if yoga offers extra relief for chronic pelvic pain, …

This study looked at whether yoga can reduce pelvic pain and improve quality of life for women with endometriosis. Sixty women who had pelvic pain for at least six months took part. They practiced yoga and reported their pain and well-being using standard questionnaires. The goal…

This study tested an experimental drug called HMI-115 in 142 women with moderate-to-severe endometriosis pain. Over 12 weeks, researchers compared the drug to a placebo to see if it safely reduces pain during periods and pelvic pain. The goal is to find a new treatment option for…

This study looked at different treatments for vestibulodynia, a long-term vulvar pain condition that affects about 1 in 6 women. Researchers compared a numbing cream, an oral medication, and a combination of both to see which worked best. 209 women took part, and the goal was to …

This study tested a drug called elagolix in 202 premenopausal women with moderate to severe endometriosis pain. The goal was to see if it reduces pain during periods and pelvic pain at other times. Participants took either elagolix or a placebo pill for 12 weeks, and researchers …

This study tested a new drug called OG-6219 in 354 women aged 18 to 49 with moderate to severe endometriosis-related pain. The goal was to see if the drug could reduce pelvic pain and check for side effects. Participants took one of three doses of OG-6219 or a placebo for several…

This study looked at whether combining yoga with pelvic floor physical therapy could help women with endometriosis feel less pain in their pelvis and during sex. 82 women took part in a 3-month program with weekly yoga and two physio sessions. The results suggest this approach ma…

This study tested a program called PEEPS for people with endometriosis-related pelvic pain. 35 participants attended weekly group sessions with a doctor, pain psychologist, physical therapist, and yoga instructor. The goal was to see if the program could reduce pain interference …

This study tested a web-based program called My Pelvic Plan for people with chronic pelvic pain, including endometriosis. 70 participants used the self-guided program to learn pain management skills. The goal was to see if it could reduce pain, improve physical function, and boos…

This study tested a dietary supplement made from parsley, rosemary, selenium, and other natural ingredients in 36 women with confirmed endometriosis. The goal was to see if it could reduce pain and the need for painkillers when added to their usual treatment. Results focused on p…

This study looked at whether the drug letrozole can reduce pain during ovarian stimulation (a key part of IVF) in people with endometriosis. 60 participants were randomly assigned to receive letrozole or a placebo. The goal was to see if letrozole helps control pain and also affe…

This study looked at whether a TENS unit, a device that sends mild electrical pulses through the skin, can ease pain during endometriosis flare-ups. Forty women with surgically confirmed endometriosis tracked their pain, medication use, and quality of life for three months withou…

This study tested whether a non-invasive brain stimulation method called tDCS can reduce chronic pelvic pain in women with endometriosis. Thirty women who had been diagnosed with endometriosis and were on hormone therapy took part. They received tDCS sessions, and researchers mea…

This study tested whether using virtual reality (VR) during a trans-vaginal ultrasound could help women with endometriosis feel less anxious and experience less pain. 155 women were randomly assigned to either use VR for relaxation during the exam or receive standard care. Resear…

This study followed over 1,400 pregnant women with endometriosis to see how the disease affects pregnancy outcomes like preterm birth and other complications. Researchers compared different types of endometriosis to better understand risks. The goal was to provide clearer informa…

This completed study looked at 2000 women with endometriosis to see if lesions and related tumors appear more often on the right or left side of the pelvis. During surgery, doctors recorded the exact location of each lesion. The goal was to better understand how endometriosis dev…

This study tested whether artificial intelligence (AI) can automatically detect endometriosis lesions during laparoscopic surgery. Researchers used video recordings from 26 patients to train and validate an AI model. The goal was to help surgeons identify diseased tissue more acc…

This study looked at 78 women to understand why endometriosis causes long-term pelvic pain. Researchers examined hormones, immune chemicals, and genes, and tested pain responses before and after surgery. The goal was to gather knowledge for better treatments, not to test a new th…

This study looked at how endometriosis affects egg development and quality. Researchers analyzed fluid from around the eggs and cells from the egg's support layer in 16 women. The goal was to find clues that could explain infertility in women with endometriosis.

This study measured 14 trace elements (like iron, selenium, lead) in blood samples from 40 women: some with endometriosis, some with ovarian or endometrial cancer, and healthy controls. Researchers wanted to see if certain elements are higher or lower in each disease group. The g…

This study looked at 56 women with endometriosis to see if severe pain during deep intercourse is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Participants completed daily pain surveys and underwent a pain-pressure…

This study looked at tissue samples from 15 women with deep endometriosis to measure nerve and blood vessel growth around painful nodules. Researchers wanted to find out how far these changes spread into healthy-looking tissue, which could help surgeons know how much tissue to re…

This study examined whether a vaginal yeast called Candida albicans is more common in women with endometriosis. Researchers compared 48 women—some with endometriosis and some without—to see if yeast overgrowth might play a role in the disease. No treatments were tested; the goal …

This study looked at whether tiny pieces of DNA floating in the blood and egg follicle fluid are higher in women with endometriosis who are doing IVF. Researchers compared 114 women with and without endometriosis to see if these DNA levels relate to egg quality and pregnancy resu…

This study looked at whether a protein called ANGPTL4 could be a better marker for endometriosis than the current CA-125 test. Researchers measured ANGPTL4 levels in the blood and pelvic fluid of 80 women—some with endometriosis and some healthy. The goal was to see if higher ANG…

This study looked at whether freezing eggs (oocyte cryopreservation) is a good option for women with benign ovarian cysts that often come back, like endometriomas or dermoid cysts. These women may need multiple surgeries, which can harm their ovaries and reduce fertility. The stu…

This study looked at whether using an ultrasound during surgery helps doctors choose the best way to remove endometriosis from the rectum. Ten adult patients with deep pelvic endometriosis took part. Doctors performed an ultrasound before and after shaving off the endometriosis t…

This study looked at how a new drug called SHR7280 interacts with six common medications in 20 healthy men. The goal was to see if SHR7280 changes how these drugs are processed in the body. Results will help doctors use SHR7280 safely for conditions like endometriosis and uterine…