ENDOMETRIOSIS

This study tests a less invasive surgery called laparoscopic sclerotherapy for ovarian cysts (endometriomas) caused by endometriosis. Instead of cutting out the whole cyst, doctors drain it and inject a solution to shrink it, which may better preserve a woman's egg supply. The st…

This study aims to develop a non-invasive diagnostic test for endometriosis, a painful condition affecting 1 in 10 women. Researchers will combine AI-enhanced ultrasound with blood, saliva, and tissue markers to detect the disease without surgery. 365 women aged 18-45 with suspec…

This study looks at how well a daily pill called relugolix combination therapy works for reducing endometriosis-related pain over 24 weeks in everyday medical practice. About 33 women aged 18-50 with confirmed endometriosis and moderate to severe pain will take the medication as …

This study tests whether a 10-week virtual mindfulness program can improve quality of life for people with endometriosis-related chronic pelvic pain. Researchers will enroll 124 adults aged 18-50 with a diagnosis of endometriosis. Participants will attend online mindfulness works…

This study looks at whether magnetic stimulation using a device called the 'Tesla chair' can help reduce pain in women with endometriosis. Many women still have pain even after surgery or medication, and painkillers may stop working. The study will include 30 women and measure pa…

This study tests whether psychological support—like individual therapy, group sessions, or a mix of both—can improve quality of life and reduce anxiety in women with endometriosis. Forty women will be randomly assigned to one of four groups, including a no-intervention control. T…

This study tests a new drug called HMI-115 to see if it can reduce pain in women with moderate to severe endometriosis. About 540 women aged 18-49 who have had surgery-confirmed endometriosis will receive either the drug or a placebo for 24 weeks, with a possible 28-week extensio…

This study tests a portable device called ActiTENS mini that uses mild electrical pulses to relieve chronic pelvic pain in women with endometriosis. About 208 women will try different stimulation strengths over 9 months to see if it reduces pain and improves quality of life. If i…

This study will test whether following a Mediterranean diet can improve quality of life and reduce pain in women with endometriosis, a chronic inflammatory condition. Researchers will enroll 104 women aged 18-45 who have been diagnosed with endometriosis and experience at least m…

This study tests a new device used at home to help manage chronic pelvic pain caused by endometriosis. About 20 adults with endometriosis and ongoing pelvic pain will use the device and report their pain levels. The goal is to see if this non-hormonal option can reduce pain and i…

This study will compare two laparoscopic hysterectomy methods—total removal of the uterus versus partial removal (leaving the cervix)—in 500 women with benign conditions like fibroids, endometriosis, or abnormal bleeding. The main goal is to see which surgery leads to better qual…

This study compares two ultrasound methods—one done before surgery (transvaginal) and one during surgery (intraoperative)—to measure bowel lesions in women with severe endometriosis. About 98 women will participate to see which method gives more accurate measurements for surgical…

This study looks at whether certain environmental chemicals (persistent organic pollutants) are linked to how severe endometriosis is. Researchers will measure these chemicals in blood samples from 650 women with endometriosis and compare them to their symptoms and disease stage.…

This study will take small pieces of diaphragm muscle from 10 women having surgery for endometriosis and grow the muscle cells in a lab. Researchers will compare these diaphragm cells to arm muscle cells to find unique features. The goal is to create a better tool for studying di…

This study looks at whether women with endometriosis who use AI tools like ChatGPT to prepare for their doctor visit have better or worse experiences. Researchers will compare satisfaction, treatment plan adherence, and communication quality between AI users and non-users. About …

This study looks at the immune system of 120 women aged 18-40 with chronic pelvic pain that hasn't improved with hormone treatment. Researchers will measure specific immune markers in the blood to see if there is a unique pattern linked to the pain. The goal is to better understa…

This study follows 100 women with deep endometriosis for 2 years to see if their lesions grow, shrink, or stay the same, and how this relates to symptoms and quality of life. Researchers will use regular ultrasounds and questionnaires to track changes. The goal is to learn whethe…

This study aims to find genetic changes that might make people with bowel endometriosis more likely to develop colorectal cancer. Researchers will compare healthy and affected bowel tissue from 30 women having surgery for deep endometriosis. The goal is to improve risk assessment…

This study looks for biological markers in the fluid and tissue of the uterus and ovaries in women with moderate to severe endometriosis. The goal is to understand why some women with endometriosis have trouble getting pregnant and to find ways to personalize fertility care. Abou…

This study looks at using ultrasound during surgery to help doctors remove endometriosis from the bowel more precisely. About 57 women with deep endometriosis will have their bowel wall thickness measured during the procedure. The goal is to see if these measurements can predict …

This study looks at why some women have repeated failed embryo implants or miscarriages. Researchers will compare uterine tissue and blood samples from 100 women with and without these issues. The goal is to find immune or bacterial differences that might explain these fertility …

This study aims to understand how the immune system and gut bacteria are involved in endometriosis, a painful condition affecting 1 in 10 women. Researchers will compare 40 women with and without endometriosis by analyzing tissue, blood, and stool samples. The goal is to find bio…

This study looks at why migraine and endometriosis often happen together in women. Researchers will follow 150 women over several menstrual cycles, tracking symptoms and taking blood samples. The goal is to find differences in a molecule called CGRP and hormone patterns that may …