Could a common diabetes drug ease endometriosis pain?

NCT ID NCT06611501

First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This pilot study tests whether metformin, a drug typically used for diabetes, can reduce pelvic pain in young women with endometriosis. Fourteen participants will take either metformin or a placebo daily for six months and track their symptoms. The goal is to see if this non-hormonal approach can improve pain and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Metformin
What this could lead to
If it works, this could offer a new non-hormonal option to ease pelvic pain in young women with endometriosis.
What could go wrong
This is a very small early-phase trial with only 14 participants. It may not show a clear benefit over placebo, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain endometriosis female reproductive system disorder Female Urogenital Diseases Pain Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

More trials for these conditions

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