Could a common diabetes drug ease endometriosis pain?

NCT ID NCT06611501

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether metformin, a drug typically used for diabetes, can reduce pelvic pain in young women with endometriosis. Fourteen participants will take either metformin or a placebo daily for six months and track their symptoms. The goal is to see if this non-hormonal approach can improve pain and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metformin

What this could lead to

If it works, this could offer a new non-hormonal option to ease pelvic pain in young women with endometriosis.

What could go wrong

This is a very small early-phase trial with only 14 participants. It may not show a clear benefit over placebo, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain endometriosis female reproductive system disorder Female Urogenital Diseases Pain Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact