COVID19
Clinical trials for COVID19 explained in plain language.
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New COVID vaccine candidate passes first safety check in small trial
⭐️ VACCINE ⭐️ CompletedThis early-stage trial tested a new COVID-19 vaccine called ABNCoV2 in 45 healthy adults who had never had COVID-19. The goal was to see if the vaccine is safe and to measure the immune response it produces. Participants received two doses, with or without an immune booster (adju…
Matched conditions: COVID19
Phase: PHASE1 • Sponsor: Radboud University Medical Center • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 29, 2026 04:15 UTC
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Mouthwash vs. COVID: does rinsing reduce virus spread?
Disease control CompletedThis early-stage study tested whether common mouthwashes can reduce the amount of SARS-CoV-2 virus that people breathe out. 34 adults with confirmed COVID-19 provided breath samples using a face mask before and after rinsing with mouthwash or water. Researchers measured viral lev…
Matched conditions: COVID19
Phase: EARLY_PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Apr 29, 2026 04:28 UTC
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Can boosting immunity help fight COVID-19? new study explores treatment options.
Disease control CompletedThis study tested different treatments and natural supplements to see if they could boost the immune system of people with COVID-19. 150 patients with symptoms and positive tests took part. Researchers measured recovery time, fever, lung inflammation, and other health markers to …
Matched conditions: COVID19
Phase: PHASE2, PHASE3 • Sponsor: Beni-Suef University • Aim: Disease control
Last updated Apr 29, 2026 04:28 UTC
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Can these drugs stop COVID-19 pneumonia from turning severe?
Disease control CompletedThis study tested two drugs, ruxolitinib and fostamatinib, in hospitalized adults with mild to moderate COVID-19 pneumonia. The goal was to see if either drug could prevent the disease from becoming severe, such as needing a breathing machine. Participants received the drug for 1…
Matched conditions: COVID19
Phase: PHASE1, PHASE2 • Sponsor: Imperial College London • Aim: Disease control
Last updated Apr 29, 2026 04:15 UTC
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Why COVID survivors struggle to breathe: new study probes muscle damage
Knowledge-focused CompletedThis study looked at 50 people who were hospitalized for COVID-19 to understand why they often feel tired and have trouble breathing after recovery. Researchers measured the strength of breathing muscles in two groups: those who needed a breathing machine and those who only neede…
Matched conditions: COVID19
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:28 UTC
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Pandemic pregnancy puzzle: new study tracks COVID immunity in moms and babies
Knowledge-focused CompletedThis study followed 105 pregnant women diagnosed with COVID-19 to learn how their immune systems responded and whether that protection passed to their babies. Researchers measured antibodies in mothers and newborns, as well as in breast milk, up to 6 weeks after birth. The goal w…
Matched conditions: COVID19
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:28 UTC
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COVID-19 ICU patients at risk for eye damage, study finds
Knowledge-focused CompletedThis study looked at eye problems in 23 COVID-19 patients in intensive care. Researchers checked for damage to the cornea, retina, and optic nerve to find and treat issues early. The goal was to prevent permanent vision loss in these very sick patients.
Matched conditions: COVID19
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:28 UTC
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Long COVID in mild cases: study tracks lingering symptoms for a year
Knowledge-focused CompletedThis study followed 300 adults who had mild to moderate COVID-19 but were not hospitalized. Researchers called them monthly for a year to see how long symptoms lasted and how they affected daily activities. The goal was to understand the course of lingering symptoms after a mild …
Matched conditions: COVID19
Sponsor: Katarina Hedin • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:27 UTC
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COVID drug combo trial tests new study design
Knowledge-focused CompletedThis completed Phase 2 trial aimed to test a master protocol that could be used to evaluate the safety and effectiveness of different drug combinations for COVID-19 patients. The study planned to enroll both hospitalized and non-hospitalized adults, but only 4 people took part. T…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Leidos Life Sciences • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:27 UTC
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COVID-19 ICU survivors: how do they recover after leaving the hospital?
Knowledge-focused CompletedThis study followed 85 adults who survived severe COVID-19 and needed intensive care. Researchers tracked their physical, mental, and thinking abilities as they moved from the hospital back home. The goal was to better understand the challenges these patients face during recovery…
Matched conditions: COVID19
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:15 UTC
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Finding the right dose: antifungal drug studied in sickest ICU patients
Knowledge-focused CompletedThis study looked at 32 adults in the ICU on ECMO life support who had severe influenza or COVID-19 and a fungal lung infection called aspergillosis. Researchers measured how the antifungal drug voriconazole behaves in the body to find the best dose for these very sick patients. …
Matched conditions: COVID19
Sponsor: University Hospitals, Leicester • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:14 UTC
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Money matters for COVID lung recovery: study reveals social gaps
Knowledge-focused CompletedThis completed study looked at 543 patients who survived severe COVID-19 lung failure (ARDS) to see how their social and economic background affected their recovery. Researchers measured breathing problems, physical ability, and mental health six months after leaving the hospital…
Matched conditions: COVID19
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:14 UTC
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Pandemic pushes gambling habits online: 120,000 players tracked
Knowledge-focused CompletedThis study looked at how the COVID-19 pandemic affected online gambling in France and Sweden. Researchers analyzed data from 120,000 gamblers to see if lockdowns and stress led to more gambling. The goal was to understand changes in gambling habits and identify groups at risk for…
Matched conditions: COVID19
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Apr 29, 2026 04:14 UTC
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Pandemic's hidden toll: ICU Workers' PTSD, anxiety, and burnout exposed
Knowledge-focused CompletedThis study looked at how working in intensive care units during the COVID-19 outbreak affected the mental health of doctors, nurses, and other caregivers. Over 700 staff members completed surveys about post-traumatic stress disorder (PTSD), anxiety, depression, and burnout. The g…
Matched conditions: COVID19
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC