COVID19
Clinical trials for COVID19 explained in plain language.
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Withdrawn trial: thyroid hormone spray for COVID lungs never tested
Disease control TerminatedThis study planned to test a thyroid hormone (T3) given directly into the lungs of COVID-19 patients with severe breathing failure (ARDS) who were on ventilators. The goal was to reduce lung fluid and improve recovery. However, the trial was withdrawn before any patients were enr…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 16, 2026 22:21 UTC
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Could a simple gas help more COVID-19 patients survive lung failure?
Disease control OngoingThis study looks at whether giving sedation through inhaled gases, instead of through a vein, helps critically ill COVID-19 patients on breathing machines. The goal is to see if this approach reduces swelling in the lungs, improves oxygen levels, and helps patients recover faster…
Matched conditions: COVID19
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Jun 16, 2026 22:20 UTC
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Can a natural compound tame COVID-19's deadly inflammation?
Disease control OngoingThis study tests whether fisetin, a natural compound found in fruits and vegetables, can help hospitalized COVID-19 patients by reducing dangerous inflammation. Researchers will give fisetin or a placebo to 80 adults aged 60+ (or younger with certain health conditions) to see if …
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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COVID-19 drug trial pulled before it even started
Disease control TerminatedThis study planned to test the safety and effectiveness of an inhaled drug called Virazole (ribavirin) in adults hospitalized with COVID-19 who had serious breathing trouble. The trial was withdrawn before enrolling any participants, so no results are available. It was a very ear…
Matched conditions: COVID19
Phase: PHASE1 • Sponsor: Bausch Health Americas, Inc. • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Could a single infusion of COVID-Fighting antibodies keep High-Risk patients out of the hospital?
Disease control TerminatedThis study tests whether a single infusion of anti-COVID-19 hyperimmune immunoglobulin (hIVIG) can improve symptoms and prevent hospitalization in adults recently diagnosed with COVID-19 who are not sick enough to be hospitalized. Participants are at higher risk due to age (55+) …
Matched conditions: COVID19
Phase: PHASE3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 16, 2026 12:48 UTC
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Experimental COVID-19 therapy targets cancer patients
Disease control OngoingThis early-stage trial tests a biologic treatment for 20 people with moderate COVID-19 who also have controlled cancer. The treatment aims to help the immune system recognize and kill the virus. Researchers will check if the virus clears and if the immune response improves.
Matched conditions: COVID19
Phase: EARLY_PHASE1 • Sponsor: Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Baby shampoo and mouthwash may fight COVID-19, study finds
Disease control OngoingThis study tested whether using a baby shampoo nasal wash and Listerine mouthwash for 4 days could lower the amount of COVID-19 virus in the nose and throat of recently infected adults aged 18-65. Participants were randomly assigned to different wash combinations, including plain…
Matched conditions: COVID19
Phase: PHASE2, PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Old TB vaccine shows promise for type 1 diabetes in long-term study
Disease control OngoingThis study tests whether repeated doses of the BCG vaccine (originally for tuberculosis) can lower blood sugar levels in adults with long-standing type 1 diabetes. About 150 adults aged 18-65 with juvenile-onset diabetes are participating over 10 years. The goal is to see if BCG …
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New camera peers inside lungs to unlock cystic fibrosis secrets
Knowledge-focused OngoingThis study tests a tiny, high-resolution camera that can be inserted into the lungs and nose to take detailed pictures of cells. Researchers want to see if this tool can help them understand early lung damage in people with cystic fibrosis. The study involves 60 adults and teens …
Matched conditions: COVID19
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:21 UTC
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COVID-19's hidden toll on organs in diabetics revealed
Knowledge-focused OngoingThis study looks at how COVID-19 may change organs like the heart, lungs, or kidneys in people who have diabetes compared to those who don't. Researchers will follow 35 adults who had COVID-19 and were discharged from the hospital 2 to 6 months earlier. The goal is to better unde…
Matched conditions: COVID19
Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:21 UTC
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Researchers track COVID-19 rules to find what works best
Knowledge-focused OngoingThis study looks at how well people follow COVID-19 rules like quarantine and social distancing, and what the side effects are on their health and finances. About 1,000 participants will fill out surveys and diaries over time. The goal is to learn how to make these public health …
Matched conditions: COVID19
Sponsor: Macfarlane Burnet Institute for Medical Research and Public Health Ltd • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Can tweaking online networks boost vaccine trust in underserved groups?
Knowledge-focused OngoingThis study explores whether changing how people connect online can help improve COVID-19 vaccine attitudes and intentions, especially for African American and Latinx communities who often face health inequities. About 4,500 adults in the US with internet access are taking part. R…
Matched conditions: COVID19
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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COVID-19 and metabolic disorders: study pulled before start
Knowledge-focused TerminatedThis study planned to observe how COVID-19 infection impacts people with inherited metabolic diseases (IMD), such as Gaucher disease or urea cycle disorders. Researchers wanted to track whether the virus caused disease worsening or metabolic imbalances. However, the study was wit…
Matched conditions: COVID19
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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University surveys online learning satisfaction during pandemic
Knowledge-focused TerminatedThis study aimed to understand how undergraduate students and teaching staff at Misr International University in Egypt felt about online learning during the COVID-19 pandemic. Over 9,000 participants were asked about their satisfaction and knowledge through questionnaires. The go…
Matched conditions: COVID19
Sponsor: Misr International University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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500 COVID survivors tracked to uncover lingering lung and breathing issues
Knowledge-focused OngoingThis study follows 500 adults who had COVID-19 to learn about long-term health problems such as breathing trouble, lung scarring, and fatigue. Researchers will track recovery patterns and look at factors like age, sex, and other illnesses. No new treatment is given; the goal is t…
Matched conditions: COVID19
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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New MRI technique reveals hidden lung damage in COVID and chronic disease
Knowledge-focused TerminatedThis study uses advanced MRI scans with special gases to see how lungs work in people with asthma, COPD, or Long COVID. Researchers will track up to 160 patients over several years to understand how these diseases change the lungs over time. The goal is to learn why some patients…
Matched conditions: COVID19
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:11 UTC
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Hospital staff antibody levels monitored for a year after AstraZeneca shot
Knowledge-focused OngoingThis study follows 200 hospital employees who received the AstraZeneca COVID-19 vaccine. Researchers measure their antibody levels at 6 weeks, 6 months, and 12 months after the second dose to see how long protection lasts. The goal is to understand the immune response and help gu…
Matched conditions: COVID19
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:17 UTC
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Gut bacteria may hold key to long COVID mysteries
Knowledge-focused OngoingThis small pilot study looks at how gut bacteria might be linked to ongoing symptoms after severe COVID-19. Researchers will measure changes in the microbiome, immune system markers, and lung function in 20 adults who had severe COVID. The goal is to find better ways to understan…
Matched conditions: COVID19
Phase: NA • Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 05, 2026 12:10 UTC
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Study to reveal COVID-19's lasting impact on asthma sufferers
Knowledge-focused TerminatedThis study looks at how COVID-19 affects people with asthma, especially their lung function and asthma control over a year. Researchers will compare two groups: asthmatics who had a severe COVID-19 infection and those who did not. The goal is to learn more so doctors can give bet…
Matched conditions: COVID19
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Knowledge-focused
Last updated Jun 02, 2026 11:58 UTC
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COVID vaccine clot study scrapped before start
Knowledge-focused TerminatedThis study aimed to collect medical information from people who developed unusual blood clots within four weeks of receiving a COVID-19 vaccine. The goal was to better understand any possible link between the vaccine and these rare events. However, the study was withdrawn before …
Matched conditions: COVID19
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 26, 2026 12:05 UTC