Breathing new life: inhaled sedation may boost COVID-19 survival

NCT ID NCT04415060

First seen Feb 18, 2026 · Last updated May 11, 2026 · Updated 9 times

Summary

This study compares two types of sedation for COVID-19 patients with lung failure who need a breathing machine. One group gets standard intravenous (IV) sedation, while the other gets inhaled gases (volatile anesthetics) that may reduce lung swelling and improve oxygen levels. Researchers will track survival, time on the ventilator, and hospital stay length. The goal is to see if inhaled sedation helps patients recover faster and eases pressure on limited drug supplies.

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Contacts and locations

Locations

  • Centre Hospitalier de l'Université de Montréal

    Montreal, Quebec, H2X 3E4, Canada

  • Grey Nuns Community Hospital

    Edmonton, Alberta, T6L 5X8, Canada

  • Hôpital Sacré-Coeur de Montréal

    Montreal, Quebec, H4J1C5, Canada

  • Institut Universitaire de Cardiologie et de Pneumologie de Quebec (IUCPQ)

    Québec, Quebec, G1V 4G5, Canada

  • London Health Sciences Centre - University Hospital

    London, Ontario, N6A 5A5, Canada

  • London Health Sciences Centre - Victoria Hospital

    London, Ontario, Canada

  • McGill University Health Centre - Royal Victoria Hospital

    Montreal, Quebec, H4A 3J1, Canada

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N3M5, Canada

  • The Ottawa Hospital

    Ottawa, Ontario, Canada

  • Universite de Sherbrooke

    Sherbrooke, Quebec, J1K 2R1, Canada

  • University Health Network - Toronto General Hospital

    Toronto, Ontario, M5G 2C4, Canada

  • University Health Network - Toronto Western Hopsital

    Toronto, Ontario, M5T 2S8, Canada

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2B7, Canada

Conditions

Explore the condition pages connected to this study.