COVID19

This study is testing whether a drug called defibrotide is safe and feasible for people with severe COVID-19 pneumonia. About 42 adults with confirmed COVID-19 and lung infiltrates will receive the drug. The main focus is on monitoring for serious side effects like bleeding and l…

This study tests whether a large dose of vitamin D3 can reduce deaths within 28 days in critically ill adults who have very low vitamin D levels. Earlier research suggested it might cut the death rate by nearly half in this specific group. The trial aims to confirm these results …

This study tests whether special immune cells (called T cells) taken from a family member who already recovered from COVID-19 can safely treat mild to moderate COVID-19 in hospitalized adults. The cells are designed to attack the virus. The trial involves 50 participants and aims…

This trial uses a flexible platform to test several potential COVID-19 treatments in adults. It aims to find safe doses and see if they help patients recover faster or avoid serious illness. The study includes both severe and mild-to-moderate cases, and new treatments can be adde…

This study tests a program to help parents in the Bronx who are feeling high stress. The program includes support and skills to reduce stress and improve how parents connect with their children. About 390 parents will take part to see if the program lowers stress and helps family…

This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, memory, and other symptoms in people with long COVID. About 91 adults who have had cognitive problems for at least 3 months after a COVID infection will recei…

This study uses a special PET-CT scan to track immune cells in people who have recovered from COVID-19. Up to 80 adults who had COVID-19 will get a tiny dose of a tracer to see where immune cells are active in their bodies. The goal is to learn more about how the immune system re…

This study looks back at 3,000 hospital patients to see if those who got a flu shot, took blood pressure meds (ACEI/ARB), antihistamines, or amantadine had better COVID-19 outcomes. Researchers want to know if these common treatments can reduce deaths or shorten hospital stays. N…

This study looks at 300,000 surgical patients in Stockholm to see how the COVID-19 pandemic impacted their recovery. Researchers will track deaths, complications, and how long people stayed in the hospital. The goal is to understand the pandemic's effects on surgical care, not to…

This study follows 1500 adults who had COVID-19 to see how the virus affects their heart and lungs over time. Researchers will track inflammation markers and breathing problems using questionnaires. The goal is to learn more about recovery, not to test a treatment.

This study is watching 6,000 pregnant women to see if getting a COVID-19 vaccine during pregnancy affects the health of the mother, baby, or infant. It compares women who got the vaccine to those who did not. The goal is to learn about risks like miscarriage, birth defects, or de…

This study collects blood and nasal samples from up to 2,000 people who have tested positive for COVID-19. Researchers aim to understand why some people get very sick while others don't, and why some have long-lasting symptoms like fatigue or memory problems. The information gath…

This study enrolls 2,000 pregnant women who had mild to severe COVID-19 and were treated with antiviral drugs or monoclonal antibodies. Researchers will compare their pregnancy outcomes and their babies' health up to 12 months old against those who did not receive these treatment…

This study follows 650 adults in Quebec to learn about the short- and long-term health problems caused by COVID-19, including damage to the heart, lungs, kidneys, and other organs. Participants include people who had mild, moderate, or severe COVID-19, as well as those who never …

This study aims to understand why some people lose their sense of smell after a COVID-19 infection and why it doesn't come back. Researchers will collect tiny samples of tissue from inside the nose of 240 people—some with smell problems and some without—to look for differences in…