Finding the right dose: antifungal drug studied in sickest ICU patients

NCT ID NCT04868188

First seen Jan 07, 2026 · Last updated Apr 29, 2026 · Updated 14 times

Summary

This study looked at 32 adults in the ICU on ECMO life support who had severe influenza or COVID-19 and a fungal lung infection called aspergillosis. Researchers measured how the antifungal drug voriconazole behaves in the body to find the best dose for these very sick patients. The goal was to improve treatment and reduce side effects.

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Contacts and locations

Locations

  • University Hospitals of Leicester

    Leicester, United Kingdom

Conditions

Explore the condition pages connected to this study.