University Hospitals, Leicester

This study is testing if a special blood filter called the HA380 can help critically ill patients who need machines to support their kidneys or lungs. The filter aims to remove harmful inflammation from the blood, which might help patients get off life support faster and spend le…

This study is testing if a newer way to pace the heart (His bundle pacing) is better and safer than the standard method (right ventricular pacing) for people with a fast, irregular heartbeat (atrial fibrillation) who also have signs of heart failure. About 100 participants will b…

This study aims to see if a quick, non-invasive bedside test can accurately measure changes in body water during pregnancy and labor. Researchers want to understand if conditions like pre-eclampsia or severe morning sickness affect hydration, and if better hydration tracking coul…

This study aims to understand how the COVID-19 pandemic changed the timing and severity of RSV (a virus causing bronchiolitis) in young UK children. It will track up to 3000 children under 2 years old who come to emergency departments with bronchiolitis symptoms. The research wil…

This study aims to discover the genetic causes of bicuspid aortic valve (BAV), a common heart defect where the aortic valve has two leaflets instead of three. Researchers will recruit 700 participants, including people with BAV and their family members, to compare their DNA and i…