Can these drugs stop COVID-19 pneumonia from turning severe?
NCT ID NCT04581954
First seen Nov 18, 2025 · Last updated Apr 29, 2026 · Updated 19 times
Summary
This study tested two drugs, ruxolitinib and fostamatinib, in hospitalized adults with mild to moderate COVID-19 pneumonia. The goal was to see if either drug could prevent the disease from becoming severe, such as needing a breathing machine. Participants received the drug for 14 days and were followed for 28 days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Imperial College Healthcare NHS Trust
London, W12 0HS, United Kingdom
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London North West University Healthcare
London, HA1 3UJ, United Kingdom
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Royal Berkshire NHS Foundation Trust
Reading, RG1 5AN, United Kingdom
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Sheffield Teaching Hospitals NHS Foundation Trust - Royal Hallamshire Hospital
Sheffield, S10 2JF, United Kingdom
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The Leeds Teaching Hospital - St James University Hospitals NHS Trust
Leeds, LS9 7TF, United Kingdom
Conditions
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