ACUTE KIDNEY INJURY

This study tested if the drug gabapentin could help protect kidney function in obese patients undergoing weight loss surgery. Researchers compared kidney health in 90 patients, measuring specific markers in the blood and urine before and after surgery. The goal was to see if usin…

This study looked at whether patients should temporarily stop a common blood pressure medication (an ACE inhibitor) before getting a coronary angiography, which is a scan of the heart's arteries. The goal was to see if stopping the pill could help protect the kidneys from a rare …

This study tested whether a new alert system could help prevent drug-related kidney injury in hospitalized adults. At eight hospitals, some doctors received standard alerts, while others got specific warnings from pharmacists about patients at high risk. The goal was to see if th…

This study aimed to find a better way to help hospitalized patients whose kidneys suddenly stop working and need dialysis. Researchers tested if waiting for specific signs before giving dialysis, instead of automatically scheduling it three times a week, could help more people re…

This pilot study tested whether using bedside ultrasound to check a patient's 'fluid tolerance' could help doctors give safer fluid treatments to hospitalized adults with sudden kidney injury. The goal was to see if this approach is practical to study and if it might help avoid g…

This study tested whether adding inhaled nitric oxide gas to standard care could protect the kidneys of patients undergoing emergency surgery for a life-threatening tear in their main artery (aortic dissection). In 106 patients, researchers compared standard treatment alone to st…

This study tested a new computer system designed to send alerts only to doctors whose hospitalized patients with sudden kidney injury were most likely to benefit. The goal was to prevent the kidney injury from getting worse, needing dialysis, or causing death, while reducing unne…

This study tested whether giving activated forms of vitamin D could prevent or lessen acute kidney injury in critically ill patients in the ICU. Researchers enrolled 150 adults at high risk for kidney problems to see if the treatment reduced the need for dialysis or death. The go…

This study tested whether a heart ultrasound (echocardiography) could help doctors better diagnose kidney problems in people with advanced liver disease (cirrhosis). Researchers examined 28 patients with sudden kidney injury to see if the ultrasound could predict who would benefi…

This study aimed to create a better tool for spotting kidney injury early in patients recovering from major heart surgery. Researchers followed 400 patients to combine blood tests and health data into a single score. The goal was to help doctors identify at-risk patients sooner s…

This study tested a new method to predict when critically ill patients receiving kidney support therapy are at risk of a dangerous drop in blood pressure. Researchers quickly removed a small amount of fluid from 20 patients and measured how their hearts responded, comparing it to…

This study tested whether inhaling nitric oxide gas during and after prolonged heart surgery could prevent acute kidney injury, a serious and common complication. It involved 250 adult patients at high risk for kidney problems due to their blood vessel health. Patients were rando…

This study tested if giving the acid-reducing drug pantoprazole around the time of heart surgery could help prevent kidney injury, a common and serious complication. It compared pantoprazole to another acid-reducing drug, famotidine, in 100 patients at higher risk for this proble…

This study looked at whether measuring a protein called vasorin in the blood could help doctors predict which patients with septic shock might develop serious kidney injury or die. Researchers measured vasorin levels in 50 critically ill patients with septic shock to see if highe…

This study looked at whether intentionally lowering a patient's blood pressure during common nose and sinus surgeries might cause hidden, early damage to the kidneys. Researchers measured special markers in the blood of 35 healthy adults before and after their surgery to detect a…

This study looked back at the medical records of 455 adults who had heart surgery using a heart-lung machine. Researchers wanted to see if certain pre-surgery blood tests, which measure inflammation and kidney function, could help predict which patients would develop sudden kidne…

This large international study aimed to better understand and predict acute kidney injury (AKI) in children who are critically ill. Researchers observed over 5,000 children in intensive care units worldwide to see if a scoring system called 'renal angina' and certain urine tests …

This study looked back at the medical records of 238 critically ill burn patients who needed a special type of kidney dialysis called CRRT. The goal was to understand how this treatment relates to patient survival and how long they stayed in the hospital. Researchers analyzed whe…

This study aimed to understand how COVID-19 causes organ damage in seriously ill patients. Researchers followed 380 intensive care patients with suspected or confirmed COVID-19, collecting daily blood and urine samples. They tracked these biomarkers alongside organ function to le…

This study looked back at medical records to see if using a special machine (ECMO) to support breathing and rest the lungs in patients with severe pneumonia had any effect on how well their kidneys worked. Researchers analyzed data from 76 adults who were treated in a single inte…

This study aimed to create a decision-making tool to help doctors identify which patients hospitalized with severe kidney injury are most likely to develop chronic kidney disease. Researchers followed 319 patients who needed dialysis for acute kidney injury to understand what fac…

This study aimed to find better ways to spot early kidney injury in people newly diagnosed with multiple myeloma who are starting a specific treatment called daratumumab. Researchers collected blood and urine samples from 20 patients to measure certain proteins that might signal …

This small study aimed to understand if taking ibuprofen before exercising in hot weather increases signs of kidney stress. Twelve healthy, active adults ran for an hour in a hot room after taking either ibuprofen or a placebo pill. Researchers measured blood and urine markers be…

This study tested a tool designed to predict which patients are at high risk for serious kidney injury after heart surgery. Researchers followed 2,500 adult heart surgery patients to see if the tool, which uses standard blood test results, could accurately forecast this common an…

This study tested whether a computer model could better predict which cancer patients would suffer kidney damage from platinum-based chemotherapy drugs. Researchers followed 77 patients in Taiwan, collecting their health data and comparing the model's predictions against the asse…

This study aimed to find better blood or urine tests to predict which patients will develop serious kidney injury after heart surgery. Researchers followed over 3,000 patients who had heart surgery and developed early signs of kidney problems. The goal was to identify tests that …