New blood filter may boost survival in septic shock patients on dialysis

NCT ID NCT07569406

First seen May 14, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This study looked back at 400 critically ill patients with septic shock and kidney failure who needed dialysis. Researchers compared those who received a special filter (Oxiris) that removes toxins and inflammation-causing substances to those who got standard filters. The goal was to see if the Oxiris filter was linked to better survival and kidney recovery. The study is complete, but because it is a retrospective review, it cannot prove cause and effect.

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Contacts and locations

Locations

  • Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oxiris filter (a special blood filter that removes toxins and inflammation-causing substances during dialysis)

What this could lead to

If the Oxiris filter is shown to improve survival and kidney recovery, it could become a standard tool for treating septic shock in intensive care.

What could go wrong

This is a retrospective study, not a controlled trial, so results may be influenced by other factors. The filter is already available, but its benefit over standard filters remains uncertain.

Conditions

The condition(s) this trial relates to.

acute kidney injury toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.