New test could predict dangerous blood pressure drops in dialysis patients

NCT ID NCT05214729

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a fast removal of 250 ml of fluid during dialysis can predict which ICU patients with acute kidney injury are at risk of unstable blood pressure. Twenty adults on mechanical ventilation and continuous dialysis underwent two different speeds of fluid removal. The goal was to see if this test could identify preload dependence, a condition where the heart relies on adequate blood volume to pump effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fast ultrafiltration challenge (rapid removal of 250 ml of fluid over 15 or 30 minutes)

What this could lead to

If successful, this test could help doctors predict which ICU patients on dialysis are at risk of unstable blood pressure, allowing safer fluid management.

What could go wrong

This is a small, early study with only 20 participants, so results may not apply to all patients. The test itself involves rapid fluid removal, which could cause temporary drops in blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Intensive Care, Croix Rousse hospital, Hospices Civils de Lyon

    Lyon, 69004, France