New test could predict dangerous blood pressure drops in dialysis patients
NCT ID NCT05214729
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether a fast removal of 250 ml of fluid during dialysis can predict which ICU patients with acute kidney injury are at risk of unstable blood pressure. Twenty adults on mechanical ventilation and continuous dialysis underwent two different speeds of fluid removal. The goal was to see if this test could identify preload dependence, a condition where the heart relies on adequate blood volume to pump effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fast ultrafiltration challenge (rapid removal of 250 ml of fluid over 15 or 30 minutes)
- What this could lead to
- If successful, this test could help doctors predict which ICU patients on dialysis are at risk of unstable blood pressure, allowing safer fluid management.
- What could go wrong
- This is a small, early study with only 20 participants, so results may not apply to all patients. The test itself involves rapid fluid removal, which could cause temporary drops in blood pressure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Intensive Care, Croix Rousse hospital, Hospices Civils de Lyon
Lyon, 69004, France
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