Hypotensive disorder

This trial tests whether using ultrasound to mark the correct spot on the back before spinal anesthesia improves success compared with the traditional method of feeling the bones. Sixty women having planned cesarean sections will be randomly assigned to either ultrasound marking …

This trial tests two standard methods of giving oxytocin, a drug that helps the uterus contract after childbirth, during planned C-sections under spinal anesthesia. One group receives a quick injection, while the other gets a slow infusion over 15 minutes. The goal is to see whic…

This study explores whether applying mild electrical stimulation to the spinal cord through the skin can improve blood pressure control in people with spinal cord injury. Participants will undergo tilt-table tests to measure immediate effects, plus 20 stimulation sessions to see …

This trial tests whether a newer anesthetic drug, ciprofol, causes fewer dangerous drops in blood pressure during anesthesia than the standard drug propofol in frail patients aged 60 and older having major abdominal surgery. Participants are randomly assigned to receive one of th…

This study tests whether keeping elderly patients on their side for 15 minutes after spinal anesthesia, instead of lying on their back, can prevent blood pressure drops. Researchers will enroll 70 high-risk patients aged 65 and older having leg surgery. The approach aims to keep …

This study tests a non-invasive device called the Hypotension Prediction Index (HPI) in 60 elderly patients (ages 65-90) undergoing shoulder surgery in a beach chair position. The device predicts when blood pressure might drop dangerously low, allowing doctors to intervene early.…

This pilot study tests whether a non-invasive brain stimulation technique called temporal interference can safely help regulate blood pressure. Researchers will enroll 25 adults with either mild untreated hypertension or hard-to-treat hypertension, as well as people with low bloo…

This study looks at whether measuring the collapsibility of the internal jugular vein in the neck using ultrasound can predict low blood pressure after general anesthesia. Researchers will measure the vein in 42 adults before gallbladder surgery and track blood pressure changes r…

This study will test a new intelligent diagnostic system for orthostatic hypotension (a sudden drop in blood pressure when standing up). The system continuously monitors blood pressure, brain blood flow, and heart signals to classify the condition more precisely. Researchers plan…

Spinal anesthesia for cesarean delivery often causes a sudden drop in blood pressure. Researchers are testing different infusion rates of phenylephrine, a drug that narrows blood vessels, to find the dose that prevents this drop in most women. The trial enrolls 200 women with ful…

This study tests whether applying mild electrical stimulation to specific acupoints on the wrist before anesthesia can prevent low blood pressure in older adults undergoing surgery. Researchers will compare high-frequency versus low-frequency stimulation in 84 participants aged 6…

This study tests a smartphone app called One.Dr to see if it can reduce the drop in blood pressure that happens when people with orthostatic hypotension stand up. About 86 adults who feel dizzy when standing will use either the real app or a sham version for 6 weeks. The goal is …

This study compares two ways of giving spinal anesthesia for planned C-sections: the standard single injection versus a sequential (two-part) injection. The goal is to see if the sequential method reduces the chance of a sudden drop in blood pressure, a common and risky side effe…

This study looks at two common methods of giving fentanyl for pain relief during labor: one injected into the spinal fluid and the other into the epidural space. The goal is to see which method causes less itching, a frequent side effect. Researchers will track itching severity a…

This study looks at whether two simple bedside tests—the Passive Leg Raising (PLR) test and the Pleth Variability Index (PVI)—can predict a temporary drop in blood pressure that sometimes happens during a lung-opening procedure called an Alveolar Recruitment Maneuver (ARM). ARM i…

This study tests whether a new device called Blood'up can help locate the radial artery in the wrist better than the traditional method of feeling for the pulse. Healthy volunteers will have arterial blood samples taken from both wrists, one using the device and the other using m…

This study asks whether nurses in geriatric departments have the knowledge needed to properly screen for orthostatic hypotension—a sudden drop in blood pressure when standing that can cause falls and other serious problems in older adults. About 30 nurses will complete a question…

This study looks at whether intentionally lowering blood pressure during elective nose surgery (rhinoplasty) causes any stress to brain cells or affects thinking abilities. Researchers will measure a protein called GFAP in the blood, which can indicate brain cell stress, and test…

This study explores whether measuring how a woman's pupils react to light before spinal anesthesia can predict dangerous drops in blood pressure during planned cesarean sections. Researchers will observe 200 healthy pregnant women and track their pupil responses and blood pressur…

This study looks at how the sedative dexmedetomidine affects the smallest blood vessels in people with septic shock, a life-threatening condition caused by severe infection. Researchers will measure blood flow in the tongue's tiny vessels and other key blood pressure indicators b…

This study will follow 1,000 adults having a routine diagnostic endoscopy (camera test of the stomach or colon) with propofol sedation. Researchers want to find out which patients are more likely to have a dangerous drop in blood pressure or oxygen levels during the procedure. Th…

This study will collect information on 1,200 emergency intubations across multiple hospitals in Taiwan. Researchers will track how often the tube is placed correctly on the first try and how often serious problems like low oxygen, low blood pressure, or cardiac arrest occur. The …

This study will check if an ultrasound of the internal jugular vein in the neck can predict a sudden drop in blood pressure during spinal anesthesia for C-section in women with preeclampsia. Researchers will measure the vein's collapsibility before surgery and track blood pressur…

This observational study will track 500 hospitalized adults aged 65 and older to see how often their blood pressure drops when standing up or after eating. Researchers will also check if these drops are linked to medications, other health problems, and future risks like falls or …

This study looks at whether fasting during Ramadan is safe for people with primary adrenal insufficiency, a condition where the adrenal glands don't make enough hormones. Researchers will monitor 35 patients for low blood sugar and dehydration during two weeks of fasting and two …

This study looks at how frailty—a state of weakness common in older adults—affects the risk of dangerously low blood pressure after anesthesia. Researchers will assess frailty in 80 elderly patients before surgery and track their blood pressure during anesthesia. The goal is to b…

This study will observe 480 adults giving birth at term who choose an epidural for pain relief. Researchers will review routine medical records to see how often blood pressure drops within 30 minutes after the epidural, how often treatment is needed, and whether the baby's heart …