Can a blood pressure pill help heart failure patients get the meds they need?
NCT ID NCT06405555
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether midodrine, a drug that raises blood pressure, can help heart failure patients with low blood pressure tolerate standard heart medications. About 56 hospitalized adults with weak heart pumps and low blood pressure will receive midodrine or usual care for up to 5 days. The goal is to see if this approach is feasible and safe, paving the way for larger studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Midodrine (oral tablet)
- What this could lead to
- If it works, this could provide a way to safely raise blood pressure in heart failure patients, allowing them to take guideline-directed heart medications that are often limited by low blood pressure.
- What could go wrong
- This is a small, early pilot study with only 56 participants, so results may not apply broadly. Midodrine may not effectively raise blood pressure or could cause side effects like high blood pressure or heart strain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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