A blood test that foresees heart rhythms?
NCT ID NCT07795892
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This study asks whether tiny RNA molecules in the blood can signal a higher risk of dangerous heart rhythms in people who have heart failure after a heart attack and use an implanted defibrillator. Researchers collect blood samples from 57 participants and compare RNA patterns between those who do and do not experience a device-treated arrhythmia during remote monitoring. The goal is to find a simple biomarker that could improve how doctors predict and manage arrhythmia risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood sample analysis for small RNA molecules (microRNAs) as biomarkers
- What this could lead to
- If certain RNA molecules reliably track dangerous heart rhythms, doctors could use a simple blood test to spot high-risk patients earlier and tailor defibrillator care.
- What could go wrong
- This is a small observational study, so the findings may not apply broadly. The RNA markers might not clearly separate who will have dangerous rhythms, and the results need confirmation in larger trials.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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57 people
The number who actually took part.
- Started
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Mar 2026
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients receiving cardiology outpatient care for post-myocardial infarction heart failure who have an implanted cardioverter-defibrillator or cardiac resynchronization therapy defibrillator and are followed through a remote monitoring program.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Post-myocardial infarction heart failure * Previous implantation of an implantable cardioverter-defibrillator or cardiac resynchronization therapy defibrillator * Participation in a remote monitoring program for the implanted device * Written informed consent Exclusion Criteria: * Age younger than 18 years * Lack of informed consent or withdrawal of consent * Concurrent participation in another study evaluating a drug or therapeutic intervention
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Provincial Hospital No. 2 in Rzeszow
Rzeszów, Podkarpackie Voivodeship, 35-301, Poland
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Other studies related to the condition(s) this trial covers.
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