Can a sedative improve blood flow in septic shock? a pilot study investigates

NCT ID NCT07657715

Not yet recruiting Knowledge-focused Sponsor: First Affiliated Hospital of Wannan Medical College Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the sedative dexmedetomidine affects the smallest blood vessels in people with septic shock, a life-threatening condition caused by severe infection. Researchers will measure blood flow in the tongue's tiny vessels and other key blood pressure indicators before and after giving the drug. The goal is to understand if dexmedetomidine helps or harms circulation in these critically ill patients, providing clues for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine
What this could lead to: If successful, this could help doctors understand how to better manage blood flow in septic shock patients, potentially improving treatment strategies.
What could go wrong: This is a very small, early pilot study with only 20 participants, so results may not apply broadly. The drug may cause low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bradycardia Critical Illness hemophilia B hypotensive disorder infectious disease with sepsis Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS SEPSIS SEPTIC SHOCK

Contacts and locations

Locations

The First Affiliated Hospital of Bengbu Medical University

Bengbu, Anhui, 233000, China
The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)

Wuhu, Anhui, 241000, China

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