New study aims to reduce itching from labor pain relief

NCT ID NCT07187427

Not yet recruiting Symptom relief Sponsor: St. Justine's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two common methods of giving fentanyl for pain relief during labor: one injected into the spinal fluid and the other into the epidural space. The goal is to see which method causes less itching, a frequent side effect. Researchers will track itching severity and other side effects like nausea and low blood pressure in 80 women giving birth vaginally.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fentanyl
What this could lead to: If this trial succeeds, it could help doctors choose the fentanyl injection method that causes less itching during labor, improving comfort for women in childbirth.
What could go wrong: This is a small, early-stage trial with only 80 participants, so results may not apply to all women. The study is not yet recruiting, and the outcome focuses on a side effect rather than a major health benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypotensive disorder Nausea Patient Satisfaction Pruritus Urinary Retention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FENTANYL ADVERSE REACTION FENTANYL ANALGESIA FETAL BRADYCARDIA DURING LABOR HYPOTENSION DRUG-INDUCED LABOR ANALGESIA NAUSEA AND VOMITTING NEURAXIAL OPIOID OPIOID ANALGESIC ADVERSE REACTION PRURITIS SATISFACTION, PATIENT TERM LABOUR URINARY RETENTION

Contacts and locations

Locations

Centre Hospitalier Universitaire de Sainte Justine

Montreal, Quebec, H3T 1C5, Canada

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