Could a simple Pill-Size switch curb opioid dependence?
NCT ID NCT07750639
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether adjusting the number of non-opioid pain pills or adding gabapentin can reduce opioid use after hand, wrist, or elbow surgery. Participants are randomly assigned to one of three pain medication regimens and report their pain levels and any need for extra prescriptions. The goal is to find a way to manage pain effectively while lowering the risk of opioid dependency.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A combination of naproxen, acetaminophen, oxycodone, and gabapentin, given in different doses and pill counts after surgery.
- What this could lead to
- If successful, this could point to safer, more effective ways to manage post-surgical pain while reducing reliance on opioids.
- What could go wrong
- The trial is relatively small and results may not apply to all surgeries. There are also risks of side effects from the medications, including nausea, dizziness, and potential for opioid dependence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AdventHealth
Orlando, Florida, 32827, United States
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