Adventhealth

This study is testing a new robotic system that uses just one small incision to perform surgeries on the liver, pancreas, stomach, and esophagus. The goal is to see if this single-port approach is safe and works well for these complex operations. The study will enroll 35 adults w…

This early-phase trial is testing whether a combination of two hormone-blocking drugs (darolutamide and relugolix) can safely shrink high-risk prostate tumors before they are surgically removed. About 30 men with aggressive prostate cancer will take the drugs for a short time bef…

This study will follow 600 adults who are already scheduled to receive a standard procedure called POEM, which uses a scope to cut tight muscles in the throat or stomach. The goal is to see how well the procedure works over time for conditions like achalasia, gastroparesis, and Z…

This study compares two methods used during colonoscopy to remove large, flat colon polyps: marking the edges before removal or using heat to treat the edges after removal. The goal is to see which method better prevents polyps from growing back. About 342 adults with polyps 20 m…

This study tracks how well a device called the DAT clip works during routine endoscopy to stop bleeding, close perforations (holes), or treat fistulas (abnormal connections) in the digestive tract. Researchers will record data from 250 adults who need this clip as part of their s…

This study tests a community-based program to help underserved adults get screened for breast, lung, and prostate cancers. Researchers will work with local resource spots to offer screenings and follow-up care. The goal is to see if this approach increases screening rates and cat…

This study is testing whether giving one dose of methadone just before total knee replacement surgery can help control pain afterward and reduce the amount of other painkillers needed. About 192 adults aged 21-75 having a knee replacement will be randomly assigned to receive meth…

This study tests whether a whole-food, plant-based diet (no added oils) can reduce painful diabetic neuropathy better than standard medication. Forty adults with type 2 diabetes and nerve pain will be randomly assigned to either the diet or medication optimization. The main goal …

This study compares two procedures to treat stomach blockage caused by cancer: a newer method using an endoscope (EUS-GJ) and traditional surgery (S-GJ). The goal is to see which is safer and works better. About 70 adults with advanced cancer will take part.

This study is testing an 8-week lifestyle program called HEAL-GYN for people who have finished chemotherapy for gynecologic cancer. The program focuses on healthy eating and physical activity to improve confidence, mental health, and overall well-being. Researchers will track cha…

This pilot study tests a retreat program called RISE for nurse managers who are experiencing burnout and stress. The program is a group workshop designed to build resilience, self-compassion, and empowerment. The study will include 16 nurse managers from AdventHealth and will mea…

This study tests whether a 4-week digital brain-training program can reduce apathy (lack of motivation) in older adults with depression. Researchers will measure changes in brain scans and apathy scores. The goal is to see if this non-drug approach can improve brain function and …

This registry study is tracking 1,000 adults who are scheduled to undergo endoscopic submucosal dissection (ESD), a procedure that removes deep tumors from the digestive tract without major surgery. Researchers want to see how well ESD works in a Western population, measuring thi…