New study tests which technique best stops colon polyps from coming back

NCT ID NCT06476145

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two methods used during colonoscopy to remove large, flat colon polyps: marking the edges before removal or using heat to treat the edges after removal. The goal is to see which method better prevents polyps from growing back. About 342 adults with polyps 20 mm or larger will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

endoscopic mucosal resection with margin marking or snare tip soft coagulation

What this could lead to

If one technique works better, it could reduce the need for repeat colonoscopies and lower the risk of colon cancer from recurring polyps.

What could go wrong

This is an early-stage comparison of two existing techniques, not a new drug or cure. The difference in recurrence rates may be small, and results may not apply to all polyp types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL ADENOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

adenomatous colon polyp colon adenoma colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AdventHealth

    RECRUITING

    Orlando, Florida, 32804, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••