Scientists hunt for blood markers that could flag opioid addiction risk before it starts

NCT ID NCT07693270

Recruiting now Knowledge-focused Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study aims to find biological markers in the blood that could predict a person's risk of developing opioid use disorder after being prescribed painkillers for a traumatic injury or surgery. Researchers will collect blood samples and health data from 100 adults admitted for trauma or certain surgeries. The goal is to develop a screening test that identifies those most vulnerable to opioid misuse, potentially allowing for safer, personalized pain management.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a blood test that identifies people at high risk for opioid addiction before they start taking pain medication.
What could go wrong: This is an early-stage observational study, not a treatment trial. The biomarkers identified may not prove accurate enough for widespread use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID CONSUMPTION OPIOID-USE DISORDER PERSISTENT OPIOID USE PERSISTENT POSTSURGICAL PAIN

Contacts and locations

Locations

University of California, San Diego
RECRUITING

La Jolla, California, 92037, United States

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