New blood pressure strategy aims to protect newborns during heart surgery

NCT ID NCT07221721

Terminated Disease control Sponsor: Jennie E Minnich Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This pilot study tests whether actively managing blood pressure during heart surgery in newborns can reduce dangerous low blood pressure episodes. About 130 newborns will be randomly assigned to either standard care or a new approach using a special monitor to keep blood pressure above a safe level. The goal is to see if this method is feasible and safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Active mean arterial pressure (MAP) management using a novel autoregulation monitoring device
What this could lead to: If successful, this approach could reduce the risk of low blood pressure during and after heart surgery in newborns, potentially improving outcomes.
What could go wrong: This is a small, early pilot study, so results may not be conclusive. The monitoring device is new and may not work as expected in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOTENSION DURING SURGERY HYPOTENSION POSTPROCEDURAL

Contacts and locations

Locations

The Cleveland Clinic

Cleveland, Ohio, 44195, United States

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