New anesthetic may protect frail elderly from dangerous blood pressure drops during surgery

NCT ID NCT07663695

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This trial tests whether a newer anesthetic drug, ciprofol, causes fewer dangerous drops in blood pressure during anesthesia than the standard drug propofol in frail patients aged 60 and older having major abdominal surgery. Participants are randomly assigned to receive one of the two drugs, and researchers monitor blood pressure closely. The goal is to find a safer option for this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
ciprofol and propofol
What this could lead to
If ciprofol causes fewer dangerous drops in blood pressure, it could become a safer choice for anesthesia in frail older patients.
What could go wrong
This is a small, single-center trial. Results may not apply to all frail elderly patients, and ciprofol may not prove safer than propofol.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • General Hospital of Ningxia Medical University

    Yinchuan, Ningxia, 750000, China

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Other studies related to the condition(s) this trial covers.