DENTAL CARIES
Clinical trials for DENTAL CARIES explained in plain language.
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Tooth decay showdown: which treatment wins for early cavities?
Disease control CompletedThis study tested two treatments for early tooth decay (white spots) in 30 teenagers aged 12 to 18. Each participant received both resin infiltration and microabrasion on different teeth to see which worked better. The goal was to improve the look of the spots and stop decay from…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Disease control
Last updated May 26, 2026 11:26 UTC
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Ancient chewing stick takes on the toothbrush in Kids' plaque battle
Disease control CompletedThis study tested whether a specially cut miswak (a natural chewing stick) removes dental plaque from children's teeth as effectively as a regular toothbrush. Eighty-two healthy kids aged 6 to 14 took part, and researchers measured plaque levels after using each tool. The goal wa…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Disease control
Last updated May 26, 2026 11:26 UTC
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Toothpaste showdown: which paste best repairs enamel?
Disease control CompletedThis study tested three toothpastes to see which one best repairs early tooth decay. Thirty adults wore a special mouth device with pieces of tooth enamel for one week per toothpaste. The goal was to measure how much the enamel hardened and how much fluoride it absorbed.
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated May 26, 2026 11:20 UTC
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New fluoride treatment may protect cancer patients' teeth during radiation
Disease control CompletedThis early study tested whether a special fluoride treatment (silver diamine fluoride) can prevent tooth decay in 56 head and neck cancer patients receiving radiation therapy. The treatment was applied by a dentist. The goal was to see if it helps keep teeth healthy during cancer…
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: Texas A & M University Baylor College Of Dentistry • Aim: Disease control
Last updated May 26, 2026 11:17 UTC
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No-Drill cavity treatments for kids: which works best?
Disease control CompletedThis study tested three cavity treatments in 60 children aged 4-8: the Hall Technique (a crown without drilling), silver diamine fluoride (a liquid that stops decay), and standard fillings. Each child received all three treatments on different teeth. The goal was to see which app…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Disease control
Last updated May 26, 2026 11:07 UTC
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Can special pastes stop aligners from damaging teeth?
Disease control CompletedThis study tested three different products (a special toothpaste, a nano-hydroxyapatite gel, and a fluoride varnish) against regular fluoride toothpaste to see which best prevents white spots and early decay around the small attachments glued to teeth during clear aligner treatme…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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New cement could save teeth from decay
Disease control CompletedThis study tested a new dental cement called ALBO-MPCA in 20 adults with cavities but healthy tooth nerves. The cement was placed directly on the nerve to help the tooth heal and form a protective layer. The goal was to see if it is safe and effective at repairing teeth without c…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Albos d.o.o. Beograd • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New filling material could save more teeth from root canals
Disease control CompletedThis study tested two types of dental fillings—bioactive and standard—for deep cavities in permanent molars. Fifty adults received treatment using a gentle technique that removes only decayed tissue. Researchers checked tooth health, pain, and filling durability over 18 months to…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Tooth-Colored fillings face off: which lasts longer?
Disease control CompletedThis study tested two ways to fill cavities in back teeth: direct composite fillings (applied directly into the tooth) and indirect composite fillings (made in a lab and then cemented in). 90 adults with cavities participated. The goal was to see which type holds up better over t…
Matched conditions: DENTAL CARIES
Sponsor: Recep Tayyip Erdogan University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New tooth-filling material may save more baby teeth from extraction
Disease control CompletedThis study tested a new material (Biodentine) against a standard one (Metapex) for treating deep cavities in baby teeth that have caused irreversible pulpitis (nerve infection). 28 children aged 4-9 received one of the two treatments. The goal was to see which better relieved pai…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mohamed Ahmed Hamdi Abo El Yamin • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Toothpaste showdown: baking soda formula may help heal cavities
Disease control CompletedThis study tested whether a toothpaste containing fluoride and baking soda can repair early signs of tooth decay better than regular fluoride toothpaste or a toothpaste without fluoride. 31 healthy adults wore a dental device with pieces of tooth enamel for 9 days, brushing with …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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No-drill cavity treatment tested in 104 kids
Disease control CompletedThis study tested a liquid called silver diamine fluoride (SDF) that is painted onto cavities to stop them from getting worse. 104 children aged 1.5 to 8 years with cavities in baby teeth were treated with SDF every six months, with or without extra fluoride varnish every three m…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Beaty Dent • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Light-Activated tooth treatment shows promise for Kids' cavities
Disease control CompletedThis study looked at 40 children aged 4-9 with cavities in their baby molars. After removing the decay, dentists applied a liquid called silver diamine fluoride (SDF) to stop remaining cavity germs. Half the kids also got a blue LED light shined on the tooth for 20 seconds. The g…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Çanakkale Onsekiz Mart University • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New study tests best way to stop cavities in Kids' teeth
Disease control CompletedThis study tested three treatments for early, non-cavity tooth decay in children aged 4 to 9 years. The treatments were a resin sealant, a fluoride varnish, and both combined. Over 12 months, researchers checked if the decay stopped or got worse. The goal was to find the best way…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Sacide Duman • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New toothpaste shows promise in reversing early tooth decay
Disease control CompletedThis study tested a new toothpaste with fluoride to see if it could help reverse the very early stages of cavities. 47 adults wore a device with tooth enamel samples in their mouth and used the toothpaste for 2 weeks. Researchers measured how much the enamel hardened, which indic…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New approach aims to stop tooth decay from returning after Kids' dental surgery
Disease control CompletedThis study looked at whether offering families extra help from a pediatrician and social worker after a child's dental surgery under anesthesia can improve follow-up care. 89 children with severe tooth decay participated. The goal was to see if this support leads to fewer missed …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New study tests High-Tech tools to catch cavities before they start
Diagnosis CompletedThis study looked at how well different methods find early tooth decay that hasn't formed a cavity yet in children aged 6 to 14. Researchers compared a visual check with three special devices that use light or lasers. The goal is to help dentists catch decay earlier so they can t…
Matched conditions: DENTAL CARIES
Sponsor: Neslihan Atmaca • Aim: Diagnosis
Last updated May 26, 2026 11:19 UTC
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3D scanner spots Kids' cavities without poking and prodding
Diagnosis CompletedThis study tested whether a 3D intraoral scanner can detect cavities, tooth wear, and fluorosis in children's baby teeth as well as a traditional visual exam. Researchers cleaned and examined the teeth of 36 children aged 3-12, then scanned them with a 3D camera. The goal was to …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Indiana University • Aim: Diagnosis
Last updated May 26, 2026 11:16 UTC
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Cash for cavity prevention: study tests if money motivates toothbrushing
Prevention CompletedThis study tested whether offering small financial rewards to parents would encourage them to brush their young children's teeth more often, aiming to prevent cavities. 244 families with children in Early Head Start programs took part. Parents used a special Bluetooth toothbrush …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of California, San Francisco • Aim: Prevention
Last updated May 26, 2026 11:24 UTC
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Toothpaste showdown: fluoride vs. probiotics in cavity prevention for kids
Prevention CompletedThis study tested whether fluoride or probiotic toothpaste can prevent cavities in 508 children aged 4-5 years. Kids brushed twice daily for 12 months with their assigned toothpaste. Researchers also surveyed parents about brushing and diet habits to identify risk factors for too…
Matched conditions: DENTAL CARIES
Phase: PHASE4 • Sponsor: The Affiliated Hospital of Qingdao University • Aim: Prevention
Last updated May 26, 2026 11:18 UTC
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New tooth sealant technique may keep cavities away longer
Prevention CompletedThis study looked at whether using a special glass powder spray before putting on a tooth sealant helps prevent cavities and keeps the sealant on teeth longer. Researchers tested this on 96 young adults aged 17-22. The goal is to find a better way to protect back teeth from decay…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Prevention
Last updated May 18, 2026 12:00 UTC
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Video teaching for dental sealants: just as good as the real thing?
Prevention CompletedThis study tested whether dental interns can learn to place pit and fissure sealants (a coating that prevents cavities) just as well from a video as from a live demonstration. Fifty children aged 7-9 each had two molars treated by different interns trained either by video or in p…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated May 18, 2026 11:59 UTC
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New tooth crowns for kids show promise in 2-Year study
Symptom relief CompletedThis study looked at how well BioFlx crowns work for fixing cavities in children's back teeth. Twenty-eight healthy kids aged 6 to 9 got these crowns, and researchers checked their teeth and asked families how satisfied they were over 24 months. The goal was to see if the crowns …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Symptom relief
Last updated May 26, 2026 11:23 UTC
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Metal-Free crowns challenge gold standard for Kids' teeth
Symptom relief CompletedThis study tested whether new tooth-colored Bioflx crowns work as well as standard metal crowns for fixing cavities in children's back baby teeth. 36 children each received both types of crowns on different molars. Researchers checked how well the crowns stayed in place, matched …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: satish vishwanathaiah • Aim: Symptom relief
Last updated May 26, 2026 11:17 UTC
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3-Second dental fillings: a game changer for cavity repair?
Symptom relief CompletedThis study tested a new dental filling material that hardens in just 3 seconds using a special light. Researchers wanted to see if it reduces tooth pain after filling and how well the fillings hold up over time. 39 adults with cavities or old fillings that needed replacement took…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Kids and parents have a say in tooth fillings – study reveals preferences
Knowledge-focused CompletedThis completed study at Universiti Teknologi MARA looked at what parents and children prefer when it comes to filling cavities in baby molars. 140 parent-child pairs were shown four types of fillings (stainless steel crowns, amalgam, composite, and bioflex crowns) and asked which…
Matched conditions: DENTAL CARIES
Sponsor: Universiti Teknologi Mara • Aim: Knowledge-focused
Last updated May 26, 2026 11:26 UTC
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IBD patients face hidden oral health struggles, new study reveals
Knowledge-focused CompletedThis study looked at how inflammatory bowel disease (IBD) impacts oral health and daily life. Researchers compared 138 adults with IBD to people without IBD, using a questionnaire to measure oral health-related quality of life. The goal was to identify factors like medications or…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 26, 2026 11:24 UTC
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Laser vs. drill: which fights cavity germs better?
Knowledge-focused CompletedThis study looked at two common ways to remove cavities in children: using a laser or a traditional drill. The goal was to see which method better reduces certain bacteria (Streptococcus mutans and Lactobacillus) in the tooth. Thirty-two children took part, and the study measured…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Medical University of Sofia • Aim: Knowledge-focused
Last updated May 26, 2026 11:24 UTC
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Chewing gum reveals dental treatment boosts kids' chewing power
Knowledge-focused CompletedThis study looked at 100 children aged 6 to 9 with cavities to see if dental treatment improves their chewing. Kids chewed a special two-colored gum before and three months after treatment, and a computer measured how well they mixed the colors. The goal was to understand if fixi…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated May 26, 2026 11:23 UTC
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Can plant extracts in mouthwash beat cavities? small study investigates
Knowledge-focused CompletedThis study looked at whether mouth rinses containing plant extracts and fluoride can help protect teeth from cavities and erosion. Twelve healthy adults used different rinses, including a plain water placebo, while wearing dental appliances with tooth samples. The goal was to mea…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of Bern • Aim: Knowledge-focused
Last updated May 26, 2026 11:23 UTC
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Scientists hunt for cavity genes in kids
Knowledge-focused CompletedThis study looked for genetic changes that might make some children more prone to severe tooth decay. Researchers compared 390 young people with many cavities to cavity-free adults. They checked for mutations in genes that affect tooth enamel. The goal was to find if certain gene…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 11:20 UTC
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Pucker up! kissing might fight cavities, study says
Knowledge-focused CompletedThis study looked at whether kissing on the mouth can help neutralize acid in the mouth after drinking sugary or fermented drinks like soda or beer. 33 healthy adults aged 18-30 drank an acidic beverage, then either kissed their partner for 40 seconds or did not. Researchers meas…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Universidad Catolica Santiago de Guayaquil • Aim: Knowledge-focused
Last updated May 26, 2026 11:20 UTC
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Toothpaste showdown: can TheraBreath repair enamel?
Knowledge-focused CompletedThis study looked at whether TheraBreath toothpaste can help repair tooth enamel and deliver fluoride to prevent cavities. Thirty-one adults wore a dental appliance with enamel samples and tested different toothpastes. The main goal was to measure how much the enamel hardened and…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 11:19 UTC
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School water program aims to quench Kids' thirst
Knowledge-focused CompletedThis study tested a program in elementary schools to encourage kids to drink more water. Researchers worked with school staff and students to make hydration easier. They measured how well the program worked and if it improved water bottle use and health markers like cavities and …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 26, 2026 11:19 UTC
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Tooth troubles tied to shy speech in school kids
Knowledge-focused CompletedThis study looked at 184 children aged 7-12 to see if oral health problems like cavities, crooked teeth, or missing teeth affect how confident they feel when speaking. Researchers collected dental exam data and had kids fill out a survey about their speaking attitudes. The goal w…
Matched conditions: DENTAL CARIES
Sponsor: Ezgi Turkyilmaz • Aim: Knowledge-focused
Last updated May 26, 2026 11:17 UTC
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Could your Child's sleep and saliva predict cavities?
Knowledge-focused CompletedThis study looked at 73 children aged 6-12 to see if sleep problems and certain substances in saliva (like melatonin and cortisol) are linked to tooth decay and gum health. Researchers measured cavity severity, saliva properties, and sleep quality using questionnaires. The goal w…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Which dental crown works best for kids under anesthesia? new study compares options
Knowledge-focused CompletedThis study looked at two different brands of stainless steel crowns used to fix cavities in children aged 2 to 8 years old. All children had their dental work done under general anesthesia. Researchers checked how well the crowns stayed in place and kept the gums healthy, and als…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Mom or dad, stay or go? study tests best way to calm kids at the dentist
Knowledge-focused CompletedThis study looked at 72 children aged 4-7 who had never been to the dentist before and needed a filling. Researchers wanted to see if having a parent in the room, behind a barrier, or not in the room at all affected the child's anxiety and behavior during treatment. They measured…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Saliva secrets: could natural proteins predict cavities in kids?
Knowledge-focused CompletedThis study measured natural germ-fighting proteins in the saliva of 50 Turkish children aged 3-6 years, comparing those with severe tooth decay to those without. Researchers wanted to see if lower levels of these proteins might make some children more prone to cavities. The goal …
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Toothpaste showdown: prescription vs. Over-the-Counter fluoride levels measured
Knowledge-focused CompletedThis study looked at how much fluoride stays in saliva after using different toothpastes and mouthrinses. Twenty healthy adults tried four combinations of toothpaste (regular or prescription-strength) and mouthrinse (with or without fluoride). Researchers measured fluoride levels…
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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New study maps hidden factors behind Kids' cavities
Knowledge-focused CompletedThis study looked at 298 children under 6 with early tooth decay in the Hauts-de-France region. Researchers collected data through dental exams and parent questionnaires to understand what factors—like family background, dental habits, and stress—are linked to more severe cavitie…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC