Laser zaps cavity bugs better than drill?
NCT ID NCT07493278
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two ways to remove cavities in children: using a laser or a traditional drill. Researchers measured how much cavity-causing bacteria (Streptococcus mutans and Lactobacillus) remained in the tooth after each method. The goal was to see if the laser could be a less invasive alternative to drilling. The study involved 32 children and used PCR testing to check bacteria levels before and after treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Er,Cr:YSGG laser
- What this could lead to
- If successful, this could show that laser treatment is as good as or better than drilling for reducing cavity-causing bacteria, potentially leading to less painful dental procedures.
- What could go wrong
- This is a small, completed study with only 32 participants, so results may not apply to all children or cavities. The study measured bacteria levels, not long-term cavity prevention or tooth health.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
32 people
The number who actually took part.
- Started
-
Oct 2025
- Finished
-
Feb 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
8 to 15 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Lesions located in the inner half of dentin, with a visible cavity or extensive dentin lesion (≥1 mm, measured with a periodontal graded probe) * Negative response to percussion * Absence of pulpal symptoms or spontaneous/night pain * Permanent molars or premolars fully erupted Exclusion Criteria: * Lesions involving less than half of the dentin or without a visible cavity * Teeth with significant crown destruction (ICDAS 06) * Positive response to percussion, pulpal symptoms, spontaneous/night pain * Teeth with periapical changes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical University of Sofia, Faculty of Dental Medicine
Sofia, Sofia, 1431, Bulgaria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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