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New Light-Based tools could catch cavities before they start

NCT ID NCT07532291

Diagnosis Sponsor: Neslihan Atmaca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested four methods for finding early tooth decay in children aged 6 to 14. Researchers compared standard visual inspection with three special tools that use light or lasers. The goal was to see which method works best for spotting cavities that haven't yet formed a hole, so dentists can treat them sooner and less invasively.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help dentists detect early tooth decay more accurately, allowing for less invasive treatment and better preservation of tooth structure.
What could go wrong
This is a small, completed diagnostic study with 51 children. The results may not apply to all populations or settings, and the methods are compared to visual inspection, which itself has limitations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

51 people

The number who actually took part.

Started

May 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children aged 6-14 years attending the Department of Pediatric Dentistry, Marmara University, were recruited for this study. The study population included participants with at least one posterior tooth exhibiting either sound occlusal surfaces or non-cavitated occlusal caries lesions (ICDAS scores 0-2). All examinations were performed under standardized clinical conditions.

Ages

6 to 14 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Voluntary agreement to participate in the study after the research procedures have been explained. * Being between 6 and 14 years of age. * Presence of at least one posterior tooth that is either sound with an ICDAS score of 0 or exhibits a non-cavitated occlusal carious lesion classified as ICDAS scores 1 or 2. * Having an occlusal surface suitable for standardized clinical and optical evaluation using Diagnodent Pen, Diagnocam, and QLF devices. * Absence of excessive plaque accumulation on the tooth surface to allow reliable measurements. Exclusion Criteria: * Declining participation in the study. * Being younger than 6 years or older than 14 years. * Presence of cavitated carious lesions (ICDAS ≥ 3) or teeth with Class II or Class III carious involvement. * Prior restorative treatment or the presence of fissure sealants on the relevant occlusal surface, which would compromise accurate optical assessment. * Tooth surfaces with excessive plaque accumulation that would hinder proper evaluation.

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Conditions

The condition(s) this trial relates to.

dental caries enamel caries pit and fissure surface dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries Non-cavitated occlusal caries

Contacts and locations

Locations

  • Marmara Universty School of Dentistry

    Istanbul, Maltepe, 34854, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.