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Toothache after fillings? new study tests a simple solution

NCT ID NCT04248803

Symptom relief Sponsor: Tamil Nadu Dr.M.G.R.Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying Gluma desensitizer during a filling procedure can reduce immediate tooth sensitivity. 570 adults with cavities in their back molars received either the desensitizer or a standard treatment. The goal was to see if it lowered pain scores right after the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

570 people

The number who actually took part.

Started

Feb 2020

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Occlusal cavitated caries in maxillary and mandibular first and second molars Exclusion Criteria: * Occlusal caries with axial or proximal extension * Teeth with periodontal treatment within last three months * Teeth with cracks * Teeth to be taken as abutment for prosthesis * Patients with psychiatric treatment * Patients in orthodontic treatment or going to need orthodontic treatment * Patients under dentin hypersensitivity or using desensitizer treatment * Patients not willing for post treatment follow up * Patients having any other teeth with pain or sensitivity symptoms * Caries excavation with pulp exposure and post treatment sensitivity due to occusal interference in restoration

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Conditions

The condition(s) this trial relates to.

dental caries dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sensitivity, tooth

Contacts and locations

Locations

  • CSI College of Dental Sciences and Research

    Madurai, Tamil Nadu, 625 001, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.