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Tooth decay showdown: which treatment wins for white spots?

NCT ID NCT07544849

Symptom relief Sponsor: Can Tho University of Medicine and Pharmacy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two ways to treat early white spot lesions on teeth in 30 teenagers aged 12 to 18. Each participant received both a resin infiltration and a microabrasion treatment on different teeth to see which worked better. The goal was to improve the appearance and stop the spots from getting worse, with results checked right after and at 6 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resin infiltration (Icon) and microabrasion (Opalustre)
What this could lead to
If successful, this could show that one of these minimally invasive treatments is more effective at improving the look of early tooth decay spots in teenagers.
What could go wrong
This is a small, completed trial with only 30 participants, so results may not apply to everyone. The treatments only address appearance and early lesions, not advanced decay.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jul 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 12 to 18 years * Presence of at least two early caries lesions (ICDAS codes 1-2) on the labial surfaces of anterior teeth (maxillary or mandibular incisors and canines) * Patients who are willing to participate and provide informed consent (or consent from parent/guardian for minors) Exclusion Criteria: * Teeth that have undergone endodontic treatment at the study site * Teeth with existing restorations or requiring restorative treatment at the lesion site * Patients with systemic conditions or oral conditions that may affect enamel integrity or interfere with treatment outcomes * Patients who are unable to comply with follow-up visits

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Conditions

The condition(s) this trial relates to.

dental caries enamel caries smooth surface dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries Early caries lesions White spot lesions [initial caries] on smooth surface of tooth

Contacts and locations

Locations

  • Can Tho University of Medicine and Pharmacy Hospital

    Can Tho, Select State, Vietnam

More trials for these conditions

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