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New fillings aim to stop cavities from coming back

NCT ID NCT07619378

Prevention Sponsor: Jouf University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested four different dental filling materials in 120 adults at high risk for cavities. The goal was to see if newer 'bioactive' materials could prevent secondary cavities (cavities that form around the edge of a filling) better than a standard composite resin. Participants received one of four fillings and were checked over 24 months for any new decay.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental filling materials (glass ionomer cement, giomer, Cention N, and composite resin)
What this could lead to
If these bioactive fillings work better, dentists may have a new way to help prevent cavities from coming back around fillings.
What could go wrong
This is a small, completed trial in high-risk adults, so results may not apply to everyone. The materials are already in use, so the benefit over standard fillings may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

May 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-55 years * Presence of at least one primary Class I or Class II cavity in a permanent posterior tooth * High caries risk with DMFT score ≥ 4 according to the Cariogram assessment * Presence of at least 20 functional teeth * Good general health * Ability and willingness to attend follow-up and recall visits Exclusion Criteria: * Pregnant women * Patients undergoing current orthodontic treatment * Presence of severe periodontitis * Xerostomia * Known allergy to any restorative material component used in the study * Bruxism or parafunctional habits

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Secondary caries

Contacts and locations

Locations

  • College of Dentistry, Jouf University

    Sakakah, Aljouf, 72388, Saudi Arabia

More trials for these conditions

Other studies related to the condition(s) this trial covers.