Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New antibiotic paste could replace drilling for Kids' cavities

NCT ID NCT07026435

Disease control Sponsor: taymour abuawwad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new, less invasive way to treat infected baby molars in children aged 4 to 10. Instead of fully cleaning out the tooth canals (standard pulpectomy), the new method uses an antibiotic paste to kill infection without drilling. The study involved 110 children and tracked success over 12 months to see if the simpler technique works as well as the standard one.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
antibiotic paste (ciprofloxacin and metronidazole mixed with iodoform-calcium hydroxide)
What this could lead to
If successful, LSTR could offer a simpler, less invasive alternative to standard root canal treatment for children's baby teeth, reducing discomfort and treatment time.
What could go wrong
This is a small, completed study with 110 children. The technique uses antibiotics, which may not work for all infections, and long-term success compared to standard care is still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

Aug 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 10 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged 4 to 10 years. * Presence of at least one primary molar with pulpal involvement requiring endodontic treatment. * Good general health without systemic conditions. * Signed informed consent from parent or legal guardian. Exclusion Criteria: * Children with systemic diseases or immune-compromising conditions. * Known allergies to any of the materials or antibiotics used in the study. * Uncooperative behavior preventing dental treatment under normal clinical conditions. * Teeth with non-restorable crown structure or excessive root resorption.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dental caries are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

dental caries dental pulp necrosis periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries Pediatric dentistry Periapical periodontitis Primary tooth pulpectomy Pulpal necrosis

Contacts and locations

Locations

  • Atatürk University Faculty of Dentistry

    Erzurum, Yakutiye, 25240, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.