Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New filling material could help teeth heal themselves

NCT ID NCT06348953

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two types of fillings for deep cavities in back teeth: a new bioactive material and a standard non-bioactive one. Fifty adults aged 18-40 with deep cavities were treated using a technique that removes only the decayed part. The researchers checked tooth sensitivity, vitality, and filling condition over 18 months to see which material worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bioactive dental restorative resin based system
What this could lead to
If it works, this could point toward a better filling material that helps teeth heal and stay healthy longer after deep cavity treatment.
What could go wrong
This is a small, completed trial with only 50 participants, so results may not apply to everyone. The materials may not show a clear advantage over standard fillings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Jun 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * young adult patients (age: 18-40 years) of both genders. * Able to tolerate necessary restorative procedures. * Willing to sign the informed consent. * Accepts the follow-up period. * Posterior permanent tooth with occlusal proximal deep carious lesion. * Radiographically (bitewing radiograph) extending to the inner 1/3 of dentine (D3) with a radiopaque layer between the carious lesion and the pulp chamber. * Sensible teeth according to cold pulp test. Exclusion criteria: * Allergy to any restorative materials. * Patients undergoing orthodontic treatment with fixed appliances. * Pregnant women. * Patients with debilitating systemic diseases * Teeth with previous restorations. * Spontaneous pain or prolonged pain (more than 15 s) after sensitivity test (cold test), which would indicate irreversible pulpitis. * Negative sensibility tests, periapical radiolucencies and sensitivity to axial or lateral percussion. * Mobile teeth, indicating periodontal disease or trauma. * External or internal resorption. * Cervical carious lesions.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Caries; dentin are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

dental caries dentin caries Stomatognathic Diseases Tooth Demineralization tooth disorder tooth resorption

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caries; dentin Deep caries Dental caries Dental diseases Dental restoration failure of marginal integrity Teeth; lesion Tooth decay Tooth demineralization Tooth diseases

Contacts and locations

Locations

  • Faculty of Dentistry - Cairo University

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.