New gel may soothe sensitive teeth after dental work
NCT ID NCT04540835
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a calcium-phosphate desensitizer applied under composite fillings to see if it reduces post-treatment tooth sensitivity. Fifty adults with cavities received either the desensitizer or no treatment. Pain was measured using a visual scale and a numerical rating. The goal was to find a simple way to ease discomfort after dental restorations.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- calcium-phosphate desensitizer (Teethmate Desensitizer)
- What this could lead to
- If it works, this could give dentists a simple way to reduce tooth pain after getting a filling.
- What could go wrong
- This is a small, completed study with only 50 participants. The results may not apply to everyone, and the effect might be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
50 people
The number who actually took part.
- Started
-
Oct 2021
- Finished
-
Dec 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Accepting to participate 2. Being in the age range of 18-65 3. Presence of at least 12 teeth in occlusion 4. The teeth to be included in the study have natural opposite and aproximal teeth 5. The teeth to be included in the study will be vital 6. The anterior or posterior teeth to be included in the study, regardless of the deep carious cavity type, have a primary carious lesion that is estimated to be very close to the pulp during cavity preparation but the pulp will not expose (dentin thickness close to the remaining pulp is less than 2 mm) 7. In the patient's mouth, one on the right and the other on the left 4., 5. and 6. 2 teeth matching the criteria. Exclusion Criteria: * Not accepting voluntarily to participate in the study 2- Being younger than 18 years old or over 65 years old 3- Presence of spontaneous toothache or orofacial pain 4- Bruxism 5- Presence of advanced periodontal disease 6- The presence of a serious systemic disease. 7- Worn, cracked or devital teeth with enough material loss to be crowned 8- Presence of lesions in the apical region after radiographic examination 9- Exposure of pulp during cavity preparation 10- Presence of gingival recession 11- Individuals who have taken painkillers, anti-inflammatory and psychotropics in the last two weeks and are currently taking 12- Pregnancy and breastfeeding individuals 13- Individuals who are allergic to the materials to be used
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Baskent University
Ankara, Turkey (Türkiye)
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