COPD

This study compared two different combinations of three inhaled medications for people with stable COPD. Twenty-two participants tried both treatments for four weeks each to see which one better improved their lung function and breathing symptoms. The goal was to find out if one …

This study tested whether inhaling a solution containing ectoin could reduce lung inflammation and slow the decline of lung function in older women with COPD. Researchers enrolled 36 non-smoking or former smoking women aged 75-80 to use the inhalation treatment. The goal was to s…

This large, year-long study compared a new triple-drug inhaler to a standard dual-drug inhaler for people with chronic obstructive pulmonary disease (COPD). Over 3,400 participants used one of the inhalers daily to see which was better at improving breathing and reducing serious …

This study followed 661 Italian adults with moderate to severe COPD for one year while they used the Trimbow® inhaler as prescribed by their doctors. Researchers wanted to see how this medication affected patients' daily symptoms, quality of life, and how consistently they used t…

This study tested whether an 8-week home exercise and breathing program could help people with COPD. It involved 128 patients in a country with limited healthcare resources. The program aimed to reduce severe symptom flare-ups, improve how far patients could walk, and make daily …

This study tested whether giving standard vaccines (MMR or BCG) could 'train' the immune systems of people with COPD to become less inflamed. 60 participants received either one of the vaccines or a placebo saline shot. The main goal was to see if the vaccines caused beneficial, …

This study tested an experimental drug called vapendavir to see if it could reduce serious lung symptoms in people with COPD after they caught a common cold virus. Researchers gave the drug or a placebo to 52 adults with moderate COPD who were then exposed to the virus. The main …

This study tested if giving hospitalized COPD patients a strong, once-daily combination inhaler could help them recover better. Researchers wanted to see if this approach reduced the need for extra breathing treatments, shortened hospital stays, and lowered the chance of being re…

This study tested a personalized approach to reduce inhaled steroid medication in people with severe COPD. Researchers used regular blood tests to guide when to lower steroid doses, aiming to control COPD flare-ups while reducing medication side effects like pneumonia and diabete…

This large, long-term study tested whether trained village health workers could reduce deaths among working-age adults (16-60 years) in remote tribal villages in India. Over 72,000 participants were involved. The program provided education, basic treatment for common diseases lik…

This study tested whether using HEPA air purifiers at home for a year could help adults with a specific type of COPD (eosinophilic COPD) breathe better and feel better. Researchers gave 178 participants either real air purifiers or fake ones that looked and sounded the same to se…

This study tested a new method to detect early lung damage from diseases like COPD or interstitial lung disease (ILD). Researchers analyzed the carbon dioxide in participants' breath in real-time to see if they could spot structural changes in the lungs before they show up on sta…

This study tested whether a smartphone app called Hyfe Cough Tracker could help monitor and manage coughs in people with various respiratory diseases. Over 600 participants with conditions like COPD, asthma, or COVID-19 used the app to record their coughs for up to 30 days. Resea…

This study tested whether electrical stimulation of leg muscles works as well as stationary cycling for people with severe COPD during a 3-4 week rehabilitation program. Researchers enrolled 102 patients with advanced COPD to compare these two exercise approaches. The main goal w…

This study tested whether two specific breathing techniques could help people with mild COPD feel less anxious and short of breath. Sixty participants with mild COPD practiced either the Wim Hof Method or Box Breathing for eight weeks. Researchers measured their anxiety levels, b…

This study tested whether playing exercise games in a social virtual reality setting is more motivating than playing alone. It involved 86 participants, including healthy teenagers and people with conditions like stroke, COPD, and cerebral palsy. Researchers compared how motivate…

This study tested whether learning self-hypnosis could help people with severe COPD (chronic obstructive pulmonary disease) better manage their anxiety and feelings of breathlessness. 133 hospitalized patients in a pulmonary rehabilitation program were randomly assigned to learn …

This study tested whether using a simple hand fan could help people with COPD feel less short of breath and improve their mood. 59 patients were split into two groups: one used a fan for 10 minutes daily for six weeks, while the other received standard care. Researchers measured …

This study tested whether a combination of breathing muscle training and pressure therapy could help people with severe, frequently-flaring COPD. 61 participants either received this breathing training along with their usual care, or just their usual care alone. Researchers measu…

This study tested whether a gentle, non-invasive brain stimulation technique could help people with COPD feel less short of breath during a disease flare-up. Researchers enrolled 30 hospitalized patients and compared real brain stimulation to a sham (fake) treatment, alongside st…

This study tested a personalized exercise program, done partly at home and partly at a clinic, for people with chronic breathing problems like COPD or sleep apnea, and for people recovering from COVID-19. Researchers wanted to see if this 18-session program could help with common…

This study tested whether using virtual reality (VR) glasses could help patients with severe COPD (chronic lung disease) who are in the intensive care unit (ICU). Fifty patients were split into two groups: one group used VR for 30 minutes each night for a week, while the other re…

This study tested whether a simple mobile device could help older hospital patients be more active. About 130 patients with conditions like COPD, heart failure, or frailty were randomly assigned to either use the device or not. The device gave visual feedback on their movement, a…

This small pilot study tested whether a simple, 15-minute breathing exercise could help people with COPD feel less stressed and manage their symptoms better. Researchers taught the breathing technique to some participants and compared them to others who received their usual care.…

This study tested if adding simple mental tasks to standard walking and cycling exercises could help people with COPD. Over 8 weeks, researchers compared a group doing these combined 'dual-task' exercises with a group doing standard exercises alone. They wanted to see if the adde…

This study tested a new phone-based support program for older adults living with moderate to severe COPD and the family or friends who help care for them. A trained nurse coach provided guidance over the phone to help manage symptoms, plan for the future, and improve daily life. …

This study looked at whether switching to a specific triple-therapy inhaler (Trimbow) helps adults with moderate-to-severe COPD who weren't fully controlled on their current two-drug inhalers. Researchers followed over 1,300 patients in their regular doctor visits for 6 months to…

This study looked back at medical records to see if a standard outpatient breathing and exercise program helps people who have both COPD and high blood pressure in their lungs (pulmonary hypertension). Researchers compared two groups—one with both conditions and one with just COP…

This small, early-stage study tested whether a 12-week tai chi program is practical and might help people with COPD. Ten participants with moderate to severe COPD were randomly assigned to either practice tai chi or continue their usual care. Researchers wanted to see if tai chi …

This study tested whether a 12-week harmonica training program could help people with COPD. Fifteen participants learned to play the harmonica in group classes and practiced at home, aiming to strengthen their breathing muscles. Researchers measured if this musical activity reduc…

This study tested two different exercise approaches for people with COPD (chronic obstructive pulmonary disease). Researchers compared traditional breathing muscle training with exercises focused on strengthening the core (trunk) muscles. The goal was to see which method better i…

This study looked at how an online tool could help doctors better manage COPD (chronic obstructive pulmonary disease) in everyday practice. Researchers used the tool to analyze the care of 100 Dutch patients and see where treatment could be improved according to international gui…

This study tested a special breathing device to see if it could measure lung function in people experiencing a COPD flare-up. Researchers followed 41 patients, testing their lungs during the flare-up and again 6-12 weeks later during recovery. The goal was to see if this device c…

This study aimed to validate computer models of lung airflow by taking real measurements. Researchers used a special MRI scan with inhaled helium gas to map airflow in the lungs of both healthy people and people with COPD. The data helps scientists understand how lung diseases li…

This study aimed to understand if a specific type of exercise training is better for people with COPD who experience dangerous drops in blood oxygen during activity. Researchers compared two exercise methods—continuous training versus interval training (short bursts with rest)—in…

This study tested whether a specific questionnaire could detect changes in quality of life for people with COPD (chronic obstructive pulmonary disease). Researchers had 57 patients with stable COPD fill out the questionnaire before and three months after starting a new long-actin…

This study aimed to understand how different protein drink formulas affect muscle building in older adults with COPD and healthy seniors. Researchers tested drinks with casein protein, sometimes adding the amino acid leucine or carbohydrates, to see which combination best promote…

This was an early-stage study to check the safety of a new injection called 9MW1911 in healthy people. The main goal was to see how well the body tolerated the drug and to find the highest safe dose. Researchers also measured how long the drug stayed in the body and if it trigger…

This study aimed to understand and predict health risks for older adults with COPD who also have a specific condition involving muscle loss and obesity. Researchers used a simple, non-invasive body scan to measure body composition in 200 participants. The goal was to see if this …

This study looked at whether performing two walking tests, instead of the usual one, at the end of a COPD rehabilitation program gives a more accurate picture of a patient's true abilities. Researchers compared the distance walked on a first and second test by 176 patients with m…

This study aimed to see if a drop in a patient's exercise performance during a standard pulmonary rehabilitation session could act as an early warning sign for an upcoming COPD flare-up. Researchers monitored 150 adults with COPD during their rehab sessions. They looked for a lin…

This small, early-stage study aimed to understand how the immune system in the nose responds to the nasal flu vaccine in people with COPD, a chronic lung disease. Researchers compared people with COPD who get frequent symptom flare-ups to those who don't, and to healthy people, b…

This study tested whether an artificial intelligence (AI) tool could help doctors follow established treatment guidelines when discharging patients with COPD (chronic obstructive pulmonary disease). Researchers compared standard care against care where the AI reviewed cases and s…

This study aimed to discover new biological markers in the blood that could help doctors better diagnose and monitor two common lung diseases: asthma and COPD. Researchers analyzed blood samples from 205 people, including healthy volunteers and patients with these conditions. The…

This study aimed to improve inhaled medicine for asthma and COPD by understanding how patients breathe. Researchers measured the breathing patterns of 163 patients to feed into computer simulations. The goal is to see how different breathing affects where medicine lands in the lu…