Breath test may catch lung disease before standard tests do
NCT ID NCT05092035
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to find early signs of lung damage in people with COPD or ILD by analyzing carbon dioxide (CO2) in their breath in real time. Researchers aimed to detect changes before standard lung function tests show any problems. The study included 40 adults, including patients and healthy smokers and non-smokers. This is an early research step to see if the method works, not a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Mar 2020
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * all male and female patients older than 18 years who have COPD, ILD or are smokers and non smokers without pulmonary diseases. * right heart catheterization performed due to to suspected pulmonary hypertension and further clinical investigation like echocardiography, lung function testing, 6-minute walk test, laboratory testing and blood gas analysis. * written informed consent Exclusion Criteria: * contraindication for lung function testing * acute life-threatening disease (including acute myocardiac infarction, pulmonary embolism, large aortic aneurysma, pneumothorax, opthalmic, brain, abdominal or thoracic surgery within the last 4 weeks, hemoptysis).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Internal Medicine, Pulmonology
Graz, Styria, 8036, Austria
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