Colonic neoplasm

This trial tests an experimental drug called SNS-101, which targets a protein called VISTA that may help tumors evade the immune system. Researchers give SNS-101 alone or with another immunotherapy, cemiplimab, to adults with advanced solid tumors that have not responded to stand…

This phase III trial studies whether adding the drug bevacizumab (Avastin) to standard chemotherapy after surgery helps prevent cancer from returning in people with high-risk stage II colon cancer. Over 2,400 participants were randomly assigned to receive either chemotherapy alon…

This study compares giving 3 rounds of chemotherapy before surgery versus the standard approach of surgery followed by 8 rounds of chemo for people with locally advanced colon cancer. The goal is to see if the pre-surgery chemo works just as well and may allow some patients to sk…

This early-phase study tested an experimental drug called COM902, alone or with other drugs, in 94 people with advanced cancers like ovarian, lung, and colon cancer. The main goal was to check safety and find the right dose. Researchers also looked for early signs that the drug m…

This trial asks whether adding the antibody drugs bevacizumab and/or cetuximab to standard chemotherapy can help people with metastatic colorectal cancer live longer. Participants receive one of several treatment combinations, and researchers compare overall survival and progress…

This trial tests an experimental virus-based therapy called JX-594 (Pexa-Vec) in people with advanced colorectal cancer that has not responded to standard treatments. The virus is designed to infect and kill cancer cells while also stimulating the immune system. It is given alone…

This study tests a new fluorescent clip that glows under special light to help surgeons locate colon tumors during minimally invasive surgery. About 110 adults with colon cancer will be randomly assigned to receive either the clip or a standard dye injection before surgery. The g…

This study tested an experimental drug called CTX-009 in 49 adults with metastatic colorectal cancer that had worsened after two or three prior treatments. The goal was to see if the drug could shrink tumors or stop them from growing. Results will help determine if further testin…

This trial investigates a type of immunotherapy called CAR-T cells that are designed to recognize and attack cancer cells carrying a protein called CEA. The study includes adults with advanced gastric, colon, rectal, esophageal, or pancreatic cancer who have not responded to at l…

This early-phase trial tests a modified virus called JX-594 (Pexa-Vec) in people with advanced colorectal cancer that has not responded to standard treatments. The virus is designed to infect and kill cancer cells while also stimulating the immune system. The main goal is to chec…

This pilot study tests whether a purified green tea extract called EGCG can help prevent colon cancer from coming back after surgery. 51 patients who had their colon cancer removed took either the extract or a placebo. Researchers are checking for changes in DNA methylation, a ma…

This study is testing a new device called SEGER IDEA™ that helps surgeons close openings in the bowel during keyhole surgery. It is the first time this device is being used in humans. Ten adults having certain types of bowel surgery will take part. The main goal is to see if the …

This large phase III trial studied whether adding the targeted drug cetuximab to standard chemotherapy after surgery helps prevent cancer from coming back in patients with stage III colon cancer. Over 3,300 patients took part, and the study focused on those with a specific geneti…

This early-phase trial tested an experimental drug called KVA12123, given alone or with the immunotherapy Keytruda, in 40 adults with advanced solid tumors (like lung, breast, or colon cancer) that had stopped responding to standard treatments. The main goals were to check safety…

This trial tests whether a program of exercise, nutrition advice, and psychological support—started four weeks before surgery and continued afterward—can reduce complications in people having colon cancer surgery. Participants are adults over 40 with non-metastatic colon cancer w…

This phase III trial tested whether adding a monoclonal antibody called edrecolomab to surgery helps people with stage II colon cancer live longer or stay cancer-free longer. About 2,100 participants were randomly assigned to receive either the antibody or no additional treatment…

This study tested whether adding the arthritis drug Celebrex to an experimental chemo drug called EPO906 could reduce severe diarrhea in people with advanced colorectal cancer. The trial enrolled 75 patients who had already tried other treatments. The first phase found the safest…

This early-stage trial tested a new drug called AZD6244 combined with standard chemotherapies in 140 people with advanced solid tumors (breast, colon, lung, melanoma, kidney). The main goal was to see if the combination is safe and tolerable, and to find the best dose. Researcher…

This study tested whether adding the anti-inflammatory drug celecoxib to standard FOLFOX chemotherapy helps prevent cancer from returning in people with stage III colon cancer after surgery. Over 2,500 participants were randomly assigned to receive either celecoxib or a placebo a…

This registry followed 500 adults with colorectal cancer that spread to the liver. All were treated with a microwave ablation device that uses heat to destroy tumors. The goal was to see how well the device controls tumors locally over 12 months and to track any side effects. The…

This study tested a new way to reconnect the colon after removing a cancerous section using a robot. The technique uses a special double purse-string stitch and a single stapler. Thirty-nine patients with sigmoid colon cancer were included, and the study looked at how well the te…

This study tested whether a 3-year physical activity program could help prevent colon cancer from coming back in 889 patients who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. Participants were randomly assigned to either the exercise program plus…

This study tested a combination of two drugs, palbociclib and cetuximab, in 24 people with a specific type of advanced colon cancer that had spread. The goal was to see if the combo could shrink tumors or stop them from growing. Participants took palbociclib pills and received ce…

This trial tested a new approach for people with advanced gastrointestinal cancers that had stopped responding to standard treatments. Doctors removed immune cells from patients' tumors, used CRISPR gene editing to disable a gene called CISH, and then infused the modified cells b…

This early-phase study tested a combination of two drugs, regorafenib and nivolumab, in 52 people with advanced colorectal cancer that had stopped responding to other treatments. The goal was to find the safest dose and see if the combination could help control the cancer. The st…

This phase II trial tested a combination of three drugs—TAS-102, irinotecan, and bevacizumab—in 42 people with advanced colorectal cancer that had spread or couldn't be removed. The goal was to see if this mix could slow tumor growth better than standard treatments. Participants …

This study looked at whether taking daily aspirin and vitamin D, along with exercise and a low-fat diet, could help prevent colorectal cancer from returning in 16 patients who had no visible cancer but still had signs of cancer DNA in their blood. The goal was to see if these lif…

This phase II trial tested two different drug combinations in 240 people with advanced HER2-positive colorectal cancer that had spread and could not be removed by surgery. One group received the antibodies trastuzumab and pertuzumab, while the other received cetuximab (an antibod…

This study tested a combination of the targeted drug cetuximab with a strong chemotherapy cocktail (FOLFIRINOX) as a first treatment for people whose colorectal cancer had spread and could not be removed by surgery. The goal was to see if this mix could shrink tumors better than …

This phase 1 trial tested a combination of regorafenib (a targeted therapy) plus two immunotherapy drugs (nivolumab and ipilimumab) in 39 patients with advanced colorectal cancer that had spread and stopped responding to chemotherapy. The goal was to find the safest dose and chec…

This early-phase study tested a combination therapy in 15 people with colon cancer who had completed standard treatment but still had tiny amounts of cancer DNA in their blood (called minimal residual disease). The treatment used specially activated immune cells from donated umbi…

This study tested a combination of two drugs, sorafenib and bevacizumab, in 83 people with advanced colorectal cancer that had spread and was no longer responding to standard treatments. The goal was to see if this combination could stop or slow tumor growth. Participants receive…

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced colorectal, lung, breast, or prostate cancers that produce a protein called CEA. The vaccine uses a modified virus to teach the immune system to attack cancer cells making CEA. The main goals were to ch…

This study looked at whether taking vitamin D supplements can help people with stage II or III colorectal cancer who are receiving chemotherapy. The researchers measured markers of cell death and inflammation in 44 patients before and after 6 months of vitamin D. The goal was to …

This study tested whether a stronger chemotherapy combination (mFOLFIRINOX) works better than the standard one (mFOLFOX) for people with high-risk stage III colon cancer after surgery. About 792 patients took part across multiple countries. The goal was to see if the stronger com…

This study tested a smartphone app to help young adult cancer survivors (ages 18-39) lose weight. The app tracked diet and activity as part of a behavioral weight loss program. The goal was to see if this approach was practical and well-liked by participants. The study involved 6…

This study tested a combination of three drugs (encorafenib, binimetinib, and cetuximab) given before surgery to people with a specific type of colorectal cancer that has a BRAF V600E mutation. Only 2 patients took part. The goal was to see how much the tumor shrank and to check …

This early-phase trial tested a combination of two drugs—copanlisib and nivolumab—in 48 adults with advanced solid tumors, specifically a type of colorectal cancer called MSS that usually doesn't respond to immunotherapy alone. The goal was to see if the combination could shrink …

This early-phase trial tested an experimental immunotherapy called ELI-002 in 25 people with KRAS-mutated pancreatic, colorectal, lung, ovarian, or bile duct cancers who had signs of remaining disease after standard treatment. The therapy aims to train the immune system to attack…

This study looked at how well patients aged 75 and older tolerate chemotherapy after surgery for stage III colon cancer. Researchers measured changes in daily living activities and used geriatric assessments and gene tests to predict outcomes. The goal is to better identify which…

This study looked at three screening methods—colonoscopy, colon capsule endoscopy, and a fecal immunochemical test (FIT)—to detect colorectal cancer or advanced growths in people aged 45 and older who have a first-degree relative with colorectal cancer. The goal was to see if the…

This study looked at whether offering a blood test for colorectal cancer screening would be accepted by average-risk patients in Appalachian outpatient clinics. Over 200 participants were given the option of a standard screening method or a blood-based test called Shield. The goa…

This study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45-85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths compar…

This study looked at whether offering a simple blood test (GuardantSHIELD) could help more people complete colorectal cancer screening compared to usual care. Over 2,000 adults aged 45-75 who were overdue for screening took part. The main goal was to see if more people got screen…

This phase 3 trial compared colonoscopy with annual fecal occult blood tests for colorectal cancer screening in nearly 5,000 healthy adults aged 50-69. The goal was to see which method finds more early tumors and has a better balance of benefits and harms. Participants were rando…

Researchers at Hanoi Medical University are testing whether personalized meals and diet coaching help stomach and colon cancer patients who are starting chemotherapy. About 120 adults receive tailored menus in the hospital, then learn to prepare high-energy, high-protein diets at…

This study looked at two oral chemotherapy drugs, Xeloda and UFT with folinic acid, in 89 people with advanced or metastatic colorectal cancer. The main goal was to see which treatment patients preferred after trying both. The study also checked how safe each drug was. Results he…

This trial tests a nurse-assisted eHealth program for patients with heart failure or colorectal cancer. After leaving the hospital, participants use a tablet with the MyDignio app to track vital signs and symptoms, and communicate with a nurse navigator. The goal is to see if thi…

This study investigates whether a 12-week program of tai chi and qigong (called Body Mind Training) can reduce fatigue in male cancer survivors aged 55 and older. Participants are randomly assigned to the mind-body training, a light exercise-only group, or a usual-care group. Res…

This study looked at whether adding the drug nefopam to standard pain relief (morphine and paracetamol) can reduce the amount of morphine needed after major colon surgery. 80 adults having planned surgery for colon cancer or diverticulosis took part. The main goal was to measure …

This study tested whether using warm, humidified carbon dioxide gas during low-pressure laparoscopic colorectal surgery reduces pain 24 hours after the procedure. 148 adults having surgery for colon or rectal tumors (benign or malignant) took part. One group received warm, moist …

This study tested whether professional socio-aesthetics (specialized beauty and well-being care) can improve quality of life, reduce pain, and ease anxiety in adults undergoing chemotherapy for lung, breast, colon, or prostate cancer. 400 participants were randomly assigned to re…

This study tested a web app called PrehabPal designed to help frail adults aged 65 and older prepare for colon cancer surgery. The app creates a personalized prehabilitation program and offers coaching. Researchers compared it to standard written instructions in 132 participants …

This study tested whether two nurse phone calls during the first three cycles of chemotherapy could improve the emotional state and quality of life of patients with breast, colon, or rectal cancer. 274 patients were randomly assigned to receive either standard care or standard ca…

This study tested a web-based support program for people with colorectal cancer undergoing treatment. The program provided information and tips on physical, emotional, and daily-life challenges. Researchers measured whether it helped reduce symptoms and improve quality of life co…

This study tested an online educational program for cancer patients receiving chemotherapy. The program included video sessions, peer discussions, and digital materials to help with symptom management and emotional coping. Researchers compared 212 patients who used the program to…

This study tested a personalized rehabilitation program for 150 adults who finished treatment for colorectal cancer. The program connects patients with specialists like physiotherapists, dietitians, and psychologists based on their individual needs. The goal was to improve qualit…

This study tested whether an oral iron pill (ferric maltol) can improve anemia in 40 adults after colorectal cancer surgery, compared to standard care. The main goal was to see if a larger study is possible, while also checking blood iron levels. The approach is simple and aims t…

This study compared two ways to manage pain during and after colorectal surgery: a TAP block (an injection into the abdominal wall) versus epidural anesthesia (an injection near the spine). About 200 adults having elective colon or rectal surgery for cancer or diverticulitis took…

This phase 2 trial looked at whether adding acupuncture and acupressure to oral cryotherapy (sucking on ice chips) can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. 78 patients were split into two groups: one got cryotherapy alone, …

This study tested whether sending personalized text messages could help colorectal cancer survivors eat more whole grains and less refined grains. Forty-six survivors who had finished active treatment received text messages and nutrition materials. The main goal was to see if peo…

This study looked at whether listening to music for a week before colon cancer surgery can lower anxiety. 116 adults scheduled for surgery were asked to listen to music three times a day. Their anxiety levels were compared to a group that did not have a music routine. The goal is…

This study tested whether a 6-week supervised exercise program could improve quality of life and reduce fatigue in 78 breast and colon cancer patients. Participants were randomly assigned to either the exercise program or usual care, and were followed for one year. The main goal …

This study tested whether a high-flow nasal cannula (HFNC) can reduce the risk of low oxygen levels during sedated gastrointestinal endoscopy in 80 adults with high-risk obstructive sleep apnea. Participants had a STOP-Bang score of 5 or higher and were undergoing gastroscopy, co…

This study tested a therapy called Managing Cancer and Living Meaningfully (CALM) to see if it helps people with brain cancer feel less distressed. 60 adults with brain tumors or brain metastases who had high depression or death anxiety took part. The study measured how many peop…

This study compared two standard pain relief methods after colon or rectal surgery: a preperitoneal catheter that delivers local anesthetic near the surgical site, and an epidural catheter placed before surgery. Researchers measured pain scores and how much extra pain medication …

This study tested whether using augmented virtual reality (AVR) during chemotherapy can help reduce pain, stress, and anxiety while boosting self-confidence. 150 adult cancer patients in the West Bank were split into two groups: one received standard care, and the other used AVR …

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily…

Researchers at Centre Oscar Lambret are studying how immune cells get inside breast and colon tumors. They will analyze stored tumor samples from about 70 patients treated between 2005 and 2007, looking at genes and proteins on blood vessel cells that may control this process. Th…

Researchers want to learn which molecules on cancer cells the immune system attacks when checkpoint inhibitor drugs work well. They collect tumor and blood samples from adults with solid tumors who respond to these drugs, either during treatment or after surgery. The team then se…

This study examined how Mexican-American families discuss their risk for diabetes, heart disease, breast cancer, and colon cancer. Researchers interviewed 498 adults from Mexican-American households in Houston to understand how culture and family history influence health communic…

This study looks at whether obesity, measured by body mass index (BMI), affects the chances of a 'textbook outcome' after minimally invasive surgery for colorectal cancer. A textbook outcome means the surgery went smoothly with no major complications, a short hospital stay, and n…

This study investigates whether a protein called WT1 is present in colorectal cancer tissue and whether its presence relates to tumor characteristics like grade, spread, and invasion. Researchers will analyze tissue samples from 60 patients with colorectal adenocarcinoma using a …

This study tested whether iPhones and Apple Watches can reliably collect health data from people with cancer. 49 adults undergoing cancer treatment wore an Apple Watch and used an iPhone for 4 months to track activity, fatigue, and thinking skills. The goal was to see if these de…

This pilot study tested whether a mindfulness program could help reduce colorectal cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods and have had a colon polyp. Twenty-four women participated to see if the program was feasible and acceptab…

This study looks at how a surgeon's growing experience with single-incision laparoscopic surgery—a minimally invasive technique using a single small cut—affects short- and long-term results for people with rectal or sigmoid colon cancer. By analyzing past cases from one surgical …

This study looks at people who develop a leak after colorectal cancer surgery. Researchers will track which patients need emergency surgery, die within 90 days, or end up with a permanent stoma. The goal is to find factors that predict these outcomes and help guide future care.

This large Italian study investigates whether a composite measure called 'Textbook Outcome' can serve as a reliable indicator of quality in colorectal cancer surgery. Researchers will analyze data from over 6,000 patients to see if meeting six key criteria—including survival, com…

This study aims to create a simple model that uses routine clinical and lab data from the first day after colorectal cancer surgery to predict the risk of anastomotic leakage—a serious complication where the surgical connection leaks. Researchers reviewed records of 117 patients …

This study compares two ways of doing colonoscopy in people with inflammatory bowel disease (IBD) who are at higher risk for colon cancer. One method takes biopsies only from visible abnormal areas, while the other also takes random biopsies from normal-looking tissue. The goal i…

This study looked at whether using a physical activity screener, along with exercise coaching and self-monitoring, could help breast and colon cancer survivors become more active and spend less time sitting. Twenty survivors who had finished their main cancer treatment at least t…

This completed study took small tissue samples from the colons of 40 people during routine colonoscopies. Using advanced genetic techniques, researchers created a detailed map of the different cell types and their gene activity. The goal is to better understand how colon diseases…

This study looked at 140 patients who had colon cancer surgery and chemotherapy at Rouen University Hospital. The goal was to see if living farther from the hospital caused a longer wait to start chemotherapy after surgery. The findings could help improve care for patients who li…

This study looks at whether certain combinations of genetic variations, rather than a single gene, can increase the risk of colorectal cancer. Researchers will compare the DNA of 700 patients with strong family histories of the disease against 350 healthy controls. The goal is to…

This completed study tested whether a new biomarker called 'mass response' can predict how well a cancer therapy will work. Researchers collected tumor cells from 72 patients with various cancers through fluid drainage or biopsies. The goal was to see if this biomarker could guid…

This study looked at 76 adults with advanced colorectal cancer to find genetic markers that might predict how well a combination of chemotherapy (FOLFOX) and the drug bevacizumab works. The goal was to understand which patients benefit most, not to test a new cure. Participants h…

This study tested whether starting a colonoscopy with the patient lying on their back (supine) or on their left side (left-lateral) makes a difference. Researchers measured how long it took to complete the procedure, how much pain patients felt, and how difficult the procedure wa…

This completed study from West China Hospital examined tumor tissue from 100 colorectal cancer patients who had already received immunotherapy. Researchers measured levels of a protein called PHGDH to see if it was linked to how well the patients responded to treatment and how lo…

This study gave educational materials about colorectal cancer and screening to 188 adults aged 45-75 in the Tampa Bay area. Researchers used surveys to measure changes in knowledge and screening intentions. The goal was to see if education encourages people to talk to their docto…

This study looked at whether using a special balloon-assisted scope (G-Eye) together with artificial intelligence (CAD-Eye) finds more polyps than a standard colonoscopy with AI alone. About 300 people aged 50-74 who had a positive stool test took part. The goal was to see if the…

This study looked at 70 adults with colorectal cancer to see how common muscle loss (sarcopenia) is before surgery and whether it leads to more complications or longer hospital stays. Researchers measured muscle strength, mass, and physical performance. The goal is to find patien…

This completed study tested a blood test that looks for tiny cancer leftovers after surgery in 175 people with stage II or III colorectal cancer. The goal was to see if the test could identify who really needs chemotherapy. If it works, it could help personalize treatment and avo…

This study reviewed the medical records of 255 adults who had colorectal polyps removed during a colonoscopy. The goal was to find out which factors, such as how the polyp was removed or its tissue type, make it more likely to come back. Researchers also tracked any complications…

This study looked at 143 people in China who had a second surgery after rectal cancer treatment because of a leak or tumor return. Researchers wanted to find out what factors help the surgery succeed and whether patients can regain the ability to poop normally. The goal is to bet…

This completed study with 297 participants examined if offering a blood-based screening test (Guardant Shield) encourages people who previously avoided stool tests or colonoscopy to get screened for colorectal cancer. Participants were adults aged 45-75 at average risk who had no…

This study tested how well people understand genetic risk when shown different visual aids. Over 1,000 participants viewed either a single side-by-side chart or a step-by-step narrative with pictures. They then estimated their risk and answered questions about how they felt and w…

This study looked at 227 people with colorectal cancer that had spread to the lining of the belly. Researchers wanted to see if waiting longer between chemotherapy and surgery affected how long patients lived without the cancer coming back. The goal is to find the best timing for…

This study compared two types of laparoscopic surgery for early-stage colon cancer: conventional colectomy and complete mesocolic excision (CME). Researchers looked at 150 patients in Upper Egypt to see which surgery removed more lymph nodes and caused fewer complications. The go…

This completed study analyzed data from 1,500 colon cancer patients to see if a new way of classifying lymph node involvement—based on both the number and location of affected nodes and tumor deposits—can better predict survival than the current standard system. Researchers colle…

This completed study followed over 3,600 people with stage I to III colon cancer who had surgery. The goal was to learn how far cancer spreads to lymph nodes and how much bowel and tissue should be removed for the best outcome. The results could help guide surgeons in the future,…

This study tested whether an educational session at a church could help Latino adults learn more about colorectal cancer and feel more willing to join cancer clinical trials. Sixty Spanish-speaking participants watched videos and completed surveys. The goal was to understand barr…

This study tested whether sending text message reminders helps more people complete a take-home colon cancer screening test (FIT) compared to standard phone call reminders. Over 1,200 adults from NYU family health centers took part. Researchers tracked how many completed the test…

This study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…

This study tested a 12-week web-based diet program with text messages for 50 colorectal cancer survivors. The goal was to see if survivors would use the program and if it could help them eat healthier. The study did not test whether the diet changes actually prevent cancer from c…

This study asked 167 people with cancer (and their caregivers) what they value most during pharmacy consultations for oral cancer drugs. Using a survey method, researchers identified key preferences to help hospitals design better support services. The goal was to improve patient…

This study looked at how often colon cancer came back within 5 years after a specific type of surgery called Laparoscopic Complete Mesocolic Excision (LCME). Researchers followed over 2,500 patients in Denmark who had stage I, II, or III colon cancer. The goal was to understand r…

This completed study examined how immune cells (myeloid cells and their bone marrow progenitors) change in patients with newly diagnosed thyroid or colon cancer. Researchers measured inflammatory markers before and after exposing cells to agents that could 'train' them to fight t…

This completed study looked at immune cells in the blood and tumor tissue of 100 people with colon cancer. Researchers measured T cells and other white blood cells to understand the body's immune response. The goal was to gather knowledge, not to test a new treatment. Participant…

This study tested a smartphone app that uses quizzes and rewards to help people make informed choices about colorectal cancer screening. 248 adults in Italy were randomly assigned to use either the gamified app or a basic information app. The researchers measured whether particip…

This completed study looked at 1,471 colon cancer patients to see how their tumor's DNA repair status (pMMR vs dMMR) relates to lymph node spread and survival. Researchers hope to identify patients who might not need extensive lymph node removal. The study is observational and do…

This study looked at how DNA from tumors changes in the blood before, during, and after surgery for breast, prostate, or colon cancer. Thirty adults having curative surgery provided blood samples to measure these DNA levels. The goal was to understand the natural pattern of DNA c…

This study looked at whether giving cancer patients a decision aid before their doctor visit (on a smartphone) or during the visit (on paper) helps them feel more involved in treatment decisions. 274 adults with breast or colorectal cancer took part. The goal was to see which for…

This completed observational study examined the real-world use of two approved drugs, regorafenib and TAS-102 (sometimes with bevacizumab), in 818 adults with metastatic colorectal cancer that had stopped responding to other treatments. Researchers analyzed electronic health reco…

This study looked at which online messages about colon cancer screening are most convincing and likely to be shared. Over 2,200 Black and White Americans aged 45-74 rated different messages from websites. The goal was to find the best ways to encourage people to follow screening …

This study worked with American Indian communities in New Mexico to find better ways to encourage screening for breast, colon, and cervical cancers. Over 500 adults took part in focus groups, surveys, and pilot programs. The goal was to understand barriers and test simple educati…

This study compared two common positions for a digital rectal exam: lying on your side (lateral decubitus) versus lying on your back (supine). The goal was to see which position allows doctors to perform a more complete exam. The study involved 320 men with conditions like colon …

This study looked back at over 7,000 colon cancer patients who had surgery to remove their tumors. Researchers wanted to see how the cancer's stage and lymph node involvement affected whether the cancer came back and how long patients lived. By grouping patients by tumor and node…

This completed study looked at how closely eight hospitals in Rome followed Enhanced Recovery After Surgery (ERAS) protocols for 1,000 patients having colorectal surgery. ERAS is a set of steps designed to help patients recover faster after surgery. The researchers wanted to see …

This study tested an AI system called EndoStyle that can change the style of colonoscopy images to look like they came from different video processors. 40 doctors with colonoscopy experience were shown sequences of real and AI-transformed images to see if they could tell the diff…