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New combo shows promise for Hard-to-Treat colon cancer

NCT ID NCT03711058

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 32 times

Summary

This study tested a combination of two drugs, copanlisib and nivolumab, in 48 adults with advanced solid tumors that had stopped responding to standard treatments, focusing on a type of colorectal cancer called MSS. The goal was to see if the combination was safe and could shrink tumors. The study found that while some patients had stable disease, the overall response rate was limited, meaning this approach may help control but not cure the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.