Glow-in-the-Dark clip could make colon cancer surgery safer
NCT ID NCT06714292
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times
Summary
This study tests a new fluorescent clip that glows under special light to help surgeons locate colon tumors during minimally invasive surgery. About 110 adults with colon cancer will be randomly assigned to receive either the clip or a standard dye injection before surgery. The goal is to see if the clip is as good or better at pinpointing the tumor, with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fluorescent surgical marker clip
- What this could lead to
- If successful, this clip could provide a more precise and safer way for surgeons to locate colon tumors during minimally invasive surgery, potentially reducing complications.
- What could go wrong
- This is a Phase 2 trial with only 110 participants, so results are preliminary. The clip may not be more effective than the current dye method, and there are risks like allergic reactions or inaccurate placement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
110 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
19 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 19years or more * With colonic neoplasm planning minimally invasive surgery * Need localization of lesion before surgery Exclusion Criteria: * Planned total proctocolectomy * Contraindication of colonoscopy * On pregnancy or breast-feeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Cancer Center
Goyang-si, Gyeonggi-do, 10408, South Korea
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Seoul Boramae Medical Center
Seoul, 07061, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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Other studies related to the condition(s) this trial covers.
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- A 2.2 mm scope could spot cancerous tissue in minutes, not days
- Can surgeons spare nerves and still cure colon cancer?