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Prepping the body and mind before colon cancer surgery may cut recovery risks

NCT ID NCT05379205

Disease control Sponsor: Universidad de Granada Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a program of exercise, nutrition advice, and psychological support—started four weeks before surgery and continued afterward—can reduce complications in people having colon cancer surgery. Participants are adults over 40 with non-metastatic colon cancer who are not already active or on a special diet. The study compares this combined program to standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
multidisciplinary prehabilitation and rehabilitation program (exercise, nutrition, psychological support)
What this could lead to
If it works, this could point toward a standard pre- and post-surgery program that helps people recover faster and with fewer complications after colon cancer surgery.
What could go wrong
This is a relatively small trial (90 people), so results may not apply to everyone. The program is demanding and may be hard for some patients to complete.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Nov 2022

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients older than 40 years * Diagnostic of nonmetastatic colon cancer (i.e., including right, transverse, left, sigmoid, subtotal, total, and hemicolectomy) * Not participating in a nutritional/ dietary intervention * Being physical inactive (i.e., not to be participating in any physical exercise program in the last 3 months, or performing less than 600 metabolic equivalents (METS)/week of moderate-vigorous physical activity). * To be capable and willing to provide informed consent * Not to suffer from any specific condition that may impede testing of the study hypothesis or make it unsafe to engage in the multidisciplinary intervention (i.e., determined by the research staff). Exclusion Criteria: * Medical contraindication for being engaged in an exercise or dietary program. * Additional surgery planned within the 3-month intervention * History of another primary invasive cancer * Planning to receive adjuvant chemotherapy * To be pregnant * To present any of the following cardiac conditions: (i) myocardial infarction or coronary revascularization procedure within prior 3 months, (ii) uncontrolled hypertension (i.e., systolic ≥180 mmHg or diastolic ≥100 mmHg), (iii) uncontrolled arrhythmias (iv) valvular disease clinically significant, (v) decompensated heart failure or (vi) to suffer from known aortic aneurysm.

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Conditions

The condition(s) this trial relates to.

colon carcinoma colonic neoplasm colorectal cancer Motor Activity Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colon cancer Postoperative complications

Contacts and locations

Locations

  • Department of Medical Physiology, Faculty of Medicine, University of Granada

    Granada, Andalusia, 18007, Spain

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