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Massive study of 7,259 colon cancer patients reveals recurrence patterns after surgery

NCT ID NCT07167147

Knowledge-focused Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked back at over 7,000 colon cancer patients who had surgery to remove their tumors. Researchers wanted to see how the cancer's stage and lymph node involvement affected whether the cancer came back and how long patients lived. By grouping patients by tumor and node stage, they hope to find patterns that could guide better follow-up care. No new treatments were tested—this was purely an analysis of past medical records.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors better predict which colon cancer patients need more intensive follow-up after surgery, potentially catching recurrences earlier.
What could go wrong
This is a retrospective study using existing data, so it can show patterns but cannot prove cause and effect. The findings may not apply to all hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

7,259 people

The number who actually took part.

Started

Apr 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study included 7,259 patients with stage I-III colon adenocarcinoma who underwent curative resection at Chang Gung Memorial Hospital (Linkou, Taiwan) between 2006 and 2018. Patients were categorized into four groups according to tumor and nodal status: T1-3N-, T1-3N+, T4N-, and T4N+. Clinical, pathological, and survival data were collected from the institutional tumor registry for retrospective analysis.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with histologically confirmed colon adenocarcinoma * Stage I-III disease at diagnosis * Underwent curative (radical) resection at Chang Gung Memorial Hospital between 2006 and 2018 * Availability of complete clinical, pathological, and follow-up data Exclusion Criteria: * Stage IV colon cancer at initial diagnosis * Non-adenocarcinoma histology (e.g., undifferentiated carcinoma, squamous cell carcinoma, lymphoma, sarcoma) * History of other malignancies or synchronous multiple cancers * Patients who underwent only palliative surgery or local excision * Incomplete medical records or missing follow-up information

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Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colon carcinoma colonic neoplasm malignant colon neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer recurrence Colon adenocarcinoma Colon cancer Colon cancer stage I Colon cancer stage II Colon cancer stage III Survival analysis

Contacts and locations

Locations

  • Chang Gung Memorial Hospital, Linkou

    Taoyuan, Taoyuan, 33305, Taiwan

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