Iron pill shows promise for anemia after colon cancer surgery
NCT ID NCT05177484
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether an oral iron pill (ferric maltol) can improve anemia in 40 adults after colorectal cancer surgery, compared to standard care. The main goal was to see if a larger study is possible, while also checking blood iron levels. The approach is simple and aims to ease recovery, not cure the cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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40 people
The number who actually took part.
- Started
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May 2022
- Finished
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Jul 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Male or Female, aged 18+ years. * Diagnosed with histologically or radiologically diagnosed colorectal adenocarcinoma. * Anaemic at point of diagnosis of colorectal adenocarcinoma (Defined as haemoglobin 10g/L below WHO criteria: 120g/L for males and 110g/L for females, to account for a 10% fluctuation in Hb) * Undergoing surgery for colorectal cancer with curative intent. * Date of planned surgery is ≥ 14 days from date of planned initiation of recruitment. * Able (in the investigators opinion) and willing to comply with all study requirements. * Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study. Exclusion Criteria: * Patients who do not have a histological diagnosis of colorectal adenocarcinoma * Female participants who are pregnant, lactating or planning a pregnancy during the course of the study. * Patients with evidence of iron overload or disturbances in utilisation of iron as stated in the product SPC. * Previous gastric, small bowel or colorectal surgery (where ≥50% of stomach or terminal ileum has been resected) * Chemotherapeutic treatment within the last 4 weeks. * Known previous anaemia not attributable to colorectal carcinoma (i.e. anaemia in patients with well established, inflammatory disorders) * Known haematological disease. * Features necessitating urgent surgery (e.g. obstructive symptoms). * Previous allergy to intravenous or oral iron or related iron products. * Patients who are unable to consent. * Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. * Participants who have participated in another research study involving an investigational product in the past 12 weeks * Confirmed liver or lung metastases
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Royal Wolverhampton NHS Trust
Wolverhampton, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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