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Scientists create detailed map of colon cells to unlock disease secrets

NCT ID NCT05195502

Knowledge-focused Sponsor: Bispebjerg Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study took small tissue samples from the colons of 40 people during routine colonoscopies. Using advanced genetic techniques, researchers created a detailed map of the different cell types and their gene activity. The goal is to better understand how colon diseases and conditions like type 2 diabetes develop.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this detailed map of colon cells could help researchers understand how colon diseases and diabetes develop, potentially guiding future treatments.
What could go wrong
This is a small, completed observational study that only describes cells—it does not test any treatment. The findings may not directly lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jul 2022

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Citizens aged 50 to 74 are invited to partake in screening for bowel cancer every second year. Patients who accept referral based on a positive fecal immunochemical test, will be invited to participate in this study

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients referred for out-patient colonoscopy as a result of positive hemoccult. * Patients able to read and understand danish. * Patients able to give informed consent. * Patients of Scandinavian ethnicity. Exclusion Criteria: * Previous large bowel resections * Suspicion pre or intraoperatively of benign or malignant disease of the colon * Known inflammatory bowel disease. * Immuno-modulation treatment * Chemotherapy. * Daily smoking * \> 21 weekly units of alcohol * \< 18 years of age

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal carcinoma diabetes mellitus inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes Inflammatory bowel diseases Large bowel cancer

Contacts and locations

Locations

  • Bispebjerg University Hospital

    Copenhagen, 2720, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.