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Blood test may help overcome barriers to colon cancer screening

NCT ID NCT06444542

First seen Jan 06, 2026 · Last updated Jun 23, 2026 · Updated 21 times

Summary

This completed study with 297 participants examined if offering a blood-based screening test (Guardant Shield) encourages people who previously avoided stool tests or colonoscopy to get screened for colorectal cancer. Participants were adults aged 45-75 at average risk who had not completed a recommended screening. The study measured their preference for the blood test and tracked how many chose it over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Penn State College of Medicine

    Hershey, Pennsylvania, 17033, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Guardant Shield blood-based colorectal cancer screening test

What this could lead to

If successful, this could show that a simple blood test boosts screening rates in people who avoid traditional methods, potentially catching more cancers early.

What could go wrong

This is a completed behavioral study, not a treatment trial. It measures preferences and adoption rates, not health outcomes, so it won't directly prove the test saves lives.

Conditions

The condition(s) this trial relates to.

colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.