COLO-RECTAL CANCER

This early-stage study is testing a new drug called ALX2004 in people with advanced lung, head and neck, esophageal, or colorectal cancers that have not responded to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a cancer-killing payload directly t…

This study looks at people with lung, colorectal, or prostate cancer that has spread to a few spots (1 to 10). It compares starting treatment right away versus waiting 6 months. The goal is to see which approach helps people live longer and have a better quality of life. About 80…

This study tests whether artificial intelligence (AI) can help surgeons better predict risks for people having surgery for colorectal cancer. About 1,200 patients across Denmark will be split into two groups: one where the surgeon uses standard methods to assess risk, and another…

This study tests if immunotherapy drugs (cemiplimab, fianlimab, and REGN7075) can clear leftover cancer DNA in the blood of colorectal cancer patients after surgery and chemotherapy. The goal is to delay or prevent the cancer from coming back. About 79 adults with stage II/III co…

This study tests a new drug called MBRC-201 for people with advanced solid tumors (like prostate, breast, lung, colorectal, or pancreatic cancer) that have stopped responding to standard treatments. The drug is an antibody-drug conjugate, designed to deliver a cancer-killing agen…

This study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, pre-cancerous growths (adenomas), and cancers linked to Lynch syndrome at an early stage. Researchers will enroll 1,200 people who have already had a colonoscopy. The goal is to s…

This study is testing a new blood test from Natera to see how well it can detect colorectal cancer and advanced growths in people at average risk. About 25,000 adults aged 40 and older who are already scheduled for a colonoscopy will give a blood sample. The results will be compa…

This study looks at how well the Shield blood test finds colorectal cancer and advanced growths in people aged 45 to 81 who are at average risk. About 3,375 participants will take the test and then have a colonoscopy to compare results. The goal is to see if the blood test works …

This study tests whether a short training program, including a brochure and follow-up phone calls, can improve self-efficacy in patients with a permanent colostomy after colorectal surgery. Researchers will enroll 70 adults and measure confidence in stoma care and social life usi…

This study is testing a new single-port robotic system for colorectal surgeries, such as for cancer or rectal prolapse. The goal is to see if it is safe and works as well as current multi-port robots. About 25 adults will take part, and researchers will track complications and re…

This study tests whether a new type of health education—using animation videos and games—can improve how well patients prepare for a colonoscopy compared to standard education. The researchers will enroll 252 adults scheduled for a colonoscopy and measure bowel cleanliness, patie…

This study looks at how to remove barriers to colorectal cancer screening at community health centers. Researchers will talk with staff and review health records to see what works best. The goal is to find simple ways to help more people get screened.

This study is building a platform to better predict who is at risk for certain cancers (breast, colon, ovarian, melanoma, lung) and to detect if cancer comes back earlier than usual scans. Researchers will analyze blood samples from 850 patients for genetic markers and tumor cell…

This study looks at how colon cancer affects people differently based on their age and sex. Researchers will track 1,400 patients to see how long they live and if the cancer comes back. The goal is to learn more about the disease, not to test a new treatment.