COLO-RECTAL CANCER

This early-phase study tests whether adding Akkermansia probiotics to standard immunotherapy and chemotherapy can safely help patients with advanced colorectal cancer that hasn't responded to prior treatments. The trial enrolls 22 adults whose tumors are MSS/pMMR type, which typi…

This early-phase trial tests whether adding the CIMAvax-EGF vaccine to standard chemotherapy and targeted drugs can trigger an immune response against metastatic colorectal cancer. Only 2 participants with a specific gene type (RAS/BRAF wild-type) were enrolled. The main goal is …

This study tests whether combining spectral CT scans with a genetic test (MSI) can more accurately predict if colorectal cancer has spread to nearby lymph nodes. Researchers will compare the imaging results with actual tissue samples from surgery or biopsy. The goal is to improve…

This study looks at whether helping people aged 40-49 with a family history of colon cancer make informed choices about screening leads to more colonoscopies. Participants either get standard care (direct referral for colonoscopy) or a shared decision-making session where they ca…

This trial tests whether a simple blood test that looks for tumor DNA can find colorectal cancer recurrence earlier than standard CT scans. About 359 patients who had surgery for stage II or III colorectal cancer will be randomly assigned to either the blood test plus frequent PE…

This study looks at whether a CT scan can be used instead of a colonoscopy to screen for colon cancer. Researchers will compare the results of 600 adults aged 50-70 who had either a CT scan or a colonoscopy. The goal is to see if CT scans can find polyps and cancer just as effect…

This study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer. The trial will compare two follow-up options after two years: ano…