COLO-RECTAL CANCER

This study looks at people with lung, colorectal, or prostate cancer that has spread to a few spots (1 to 10). It compares starting treatment right away versus waiting 6 months. The goal is to see which approach helps people live longer and have a better quality of life. About 80…

This study tests whether artificial intelligence (AI) can help surgeons better predict risks for people having surgery for colorectal cancer. About 1,200 patients across Denmark will be split into two groups: one where the surgeon uses standard methods to assess risk, and another…

This study tests if immunotherapy drugs (cemiplimab, fianlimab, and REGN7075) can clear leftover cancer DNA in the blood of colorectal cancer patients after surgery and chemotherapy. The goal is to delay or prevent the cancer from coming back. About 79 adults with stage II/III co…

This early-phase study tests a new drug called ALX2004 in about 170 people with advanced or metastatic solid tumors (lung, head and neck, colorectal, or esophageal cancer) that have not responded to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a …

This study tests a new drug called MBRC-201 for people with advanced solid tumors (like prostate, breast, lung, colorectal, or pancreatic cancer) that have stopped responding to standard treatments. The drug is an antibody-drug conjugate, designed to deliver a cancer-killing agen…

This study is testing a blood test (called a liquid biopsy) to see how well it can find colorectal cancer, pre-cancerous growths (adenomas), and Lynch syndrome-related cancers early. Researchers will enroll 1,200 people who have already had a colonoscopy. The goal is to see if th…

This study looks at how well the Shield blood test finds colorectal cancer and advanced growths in people aged 45 to 81 who are at average risk. About 3,375 participants will take the test and then have a colonoscopy to compare results. The goal is to see if the blood test works …

This study is testing a new blood test (Natera CRC Screening Test) to see how well it can detect colorectal cancer and advanced growths in people at average risk. About 25,000 adults aged 40 and older who are already scheduled for a colonoscopy will give a blood sample before the…

This study tests a training program for people with permanent colostomies after colorectal surgery. The goal is to help them feel more confident in managing their stoma and daily life. Researchers will measure self-efficacy using a special scale. The program aims to improve quali…

This pilot study works with staff at community health centers to find better ways to increase colorectal cancer screening. Researchers will hold group discussions and look at existing health records to see what strategies work best. The goal is to make screening easier and more a…

This study is building a platform to better predict who is at risk for certain cancers (breast, colon, ovarian, melanoma, lung) and to detect if cancer comes back earlier than usual scans. Researchers will analyze blood samples from 850 patients for genetic markers and tumor cell…

This study looks at how colon cancer affects people differently based on their age and sex. Researchers will track 1,400 patients to see how long they live and if the cancer comes back. The goal is to learn more about the disease, not to test a new treatment.

This study is testing a new single-port robotic system for colorectal surgeries, such as for cancer or rectal prolapse. It involves 25 adults and aims to see if the robot is safe and effective compared to current multi-port methods. The focus is on measuring complications and rec…

This study tests whether a new app with animations and games can help people prepare better for a colonoscopy compared to standard instructions. Researchers will enroll 252 adults and measure how clean the bowel is and how satisfied patients are. The goal is to see if the app imp…