Hit cancer early or wait? major trial tests timing of radiation for spread tumors

NCT ID NCT06563388

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether treating 1 to 10 metastatic tumors right away with precise radiation improves survival compared to waiting 3 months. It includes 800 adults with lung, colorectal, or prostate cancer that has spread to a few spots. Participants are randomly assigned to get radiation immediately or after a delay, while both groups receive standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stereotactic ablative radiotherapy (SABR/SBRT)
What this could lead to
If immediate treatment improves survival or delays the need for hormone therapy, this could change standard care for patients with a few metastatic tumors.
What could go wrong
This is a single-center trial, and results may not apply to all patients. Delayed treatment might not worsen outcomes, and quality-of-life differences could be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roswell Park Comprehensive Cancer Center

    RECRUITING

    Buffalo, New York, 14263, United States

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Other studies related to the condition(s) this trial covers.