OLIGOMETASTASIS

This large trial is testing if adding a targeted local treatment to standard drug therapy helps people with advanced breast cancer that has spread to only a few spots in the body. After 12 weeks of initial drug treatment, 340 participants will be randomly assigned to either conti…

This large, late-stage trial is testing whether immediately using aggressive treatments like radiation to destroy all visible cancer spread sites helps people live longer than waiting six months. It's for adults with lung, prostate, or colorectal cancer that has spread to 10 or f…

This study aims to find out if a precise, high-dose radiation treatment called SBRT can help control breast cancer that has spread to only a few other places in the body. Researchers will look back at the medical records of 300 patients who received this treatment to see if it im…

This study is testing a faster way to plan and deliver a precise type of radiation therapy (SBRT) for people whose cancer has spread to up to five spots in their body. Instead of scheduling a separate planning scan and waiting over a week, doctors will use a recent diagnostic sca…

This study is for people with esophageal or stomach cancer that has spread to only a few other places in the body. It compares two approaches: standard chemotherapy alone versus a more aggressive strategy that adds targeted radiation and possibly surgery to the chemotherapy. The …

This VA study is testing if adding targeted radiation or surgery to standard drug therapy works better for controlling prostate cancer that has spread to a few spots. It will involve about 464 Veterans whose cancer has returned or spread to 1-10 locations. The goal is to see if t…

This study is creating a registry to collect information about short-term side effects in patients receiving targeted, high-dose radiation for cancer that has spread. It will enroll 300 adults with metastatic cancer who are planning to receive, currently receiving, or have comple…